Case presentation: T.V, F, 4 years-old. Consanguineous parents. G1PN1A0. At birth, diagnosis of Congenital Retinal Detachment. Hypotonic patient, at 6 months age, she had her first seizure, since then using anti-seizure drugs without good control. Positive family history for epilepsy and intellectual disability. Patient head support. It has hypertelorism, high palate, corneal opacity. Grade 2 s...

purpose : to describe the survival characteristics and prognostic factors of patients with retinoblastoma in a referral center in iran methods : from medical records, we retrospectively analyzed the data of 139 consecutive children diagnosed in our hospital between 1991 and 2001 as having retinoblastoma. information on gender, laterality, age at diagnosis, presenting signs, tumor staging, treat...

Retinoblastoma is a rare eye tumor of childhood that arises in the retina. It is the most common intraocular malignancy of infancy and childhood; with an incidence of 1/15,000-20,000 live births. The two most frequent symptoms revealing retinoblastoma are leukocoria and strabismus. Iris rubeosis, hypopyon, hyphema, buphthalmia, orbital cellulites and exophthalmia may also be observed. Sixty per...

PURPOSE Retinoblastoma (RB) is a rare intraocular malignant tumor of the developing retina with an estimated incidence of 1:20,000 live births in children under the age of 5 years. In addition to the abnormal whitish appearance of the pupil or leukocoria, strabismus has also been reported as a clinical symptom of the disease. RB1 is the first cloned tumor suppressor gene, and mutational inactiv...

PURPOSE To investigate the clinical characteristics of X-linked retinoschisis (XLRS) and identify genetic mutations in Taiwanese patients with XLRS. METHODS This study included 23 affected males from 16 families with XLRS. Fundus photography, spectral domain optical coherent tomography (SD-OCT), fundus autofluorescence (FAF), and full-field electroretinograms (ERGs) were performed. The coding...

Childhood blindness has an adverse effect on growth, development, social, and economic opportunities. Severe visual impairment (SVI) and blindness in infants must be detected as early as possible to initiate immediate treatment to prevent deep amblyopia. Although difficult, measurement of visual acuity of an infant is possible. The causes of SVI and blindness may be prenatal, perinatal, and pos...

Blixt, M. 2017. Keeping up with retinal photoreceptors and horizontal cells. Labelling and mapping of cells in the normal and diseased embryonic chicken retina. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1302. 62 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9825-2. The childhood eye cancer retinoblastoma originates from the retina and i...

2 Eye Hospital. His left eye had been noted to be clinically small with an abnormal pupil and a white pupillary reflex. His general practitioner and the family were under the impression that there was a strong family history of retinoblastoma. An examination was performed under anaesthesia. The right eye was normal. The left eye was microphthalmic with a horizontal corneal diameter of 9-5 mm (r...

The aim of this study was to look at the visual outcome and treatment complications of children diagnosed with Retinoblastoma during the years 1985-2003 inclusive. A retrospective review of all patients records was performed. Patient characteristics, treatment methods and complications were recorded. Twenty eight children presented to Temple street Hospital between 1985-2003. Six of these infan...

We report on a 7-month-old boy who suffered from retinoblastoma with presentation of a white pupillary reflex in his right eye. Initial examination showed a large subretinal and intraretinal mass nasally with extensive vitreous seeding of tumor cells (Group Vb in the Reese-Ellsworth classification). External beam radiation therapy (EBRT) was applied in hopes of preserving the eye, and significa...