The results of a study of a screening test for urinary tract infection (UTI) in infants under 18 months is reported. Two hundred and forty three urine specimens were tested in the laboratory using AMES Multistix 8SG reagent strips read by photometer. The strips included three potential markers for urinary tract infection: leucocyte esterase, nitrite, and protein. The predictive value of a posit...

The highly polymorphic and complex system of human leucocyte antigens known as HL-A has been intensively investigated in recent years.1,2 It seems to be widely understood that the research is very actively engaged at the present time in the task and prospect of tissue typing for selecting donors and recipients for organ transplantation in man. In the near future, however, one may anticipate the...

This study investigated the immunotoxic potentials of raw and simulated leachates from Olushosun municipal solid waste landfill in rat using quantitative leucocyte and differential counts. Blood samples of rats intraperitoneally exposed to 1 – 25 % concentrations of each of the leachate samples for 48 hours were examined post treatment for leukocyte and differential counts. Compared to the nega...

Total body potassium (40K) and leucocyte potassium measurements were carried out on 19 patients with stable but decompensated cirrhosis maintained on diuretics for previous ascites. Of 13 patients receiving spironolactone alone none had a total body potassium below the expected lower limit of normal, whereas, of six receiving additional frusemide, two had low values. The results for leucocyte p...

The effects of smoking and age on the results of hematologic tests were determined in a group of 429 healthy male workers. The results obtained were as follows: 1) The values of total leucocyte count (x10(9)/l), neutrophil count (x10(9)/l), lymphocyte count (x10(9)/l), monocyte count (x10(9)/l), hemoglobin (g/l), hematocrit, mean corpuscular volume (MCV; fl), mean corpuscular hemoglobin (MCH; p...

Endothelial dysfunction is a hallmark of systemic inflammatory response underlying multiple organ failure. Here we report a novel function of DHHC-containing palmitoyl acyltransferases (PATs) in mediating endothelial inflammation. Pharmacological inhibition of PATs attenuates barrier leakage and leucocyte adhesion induced by endothelial junction hyperpermeability and ICAM-1 expression during in...

Quantitative leucocyte mobilisation in vivo and the in-vitro random migration, chemotaxis, phagocytosis, and oxidative metabolic activity were studied in 15 patients with rheumatoid arthritis (RA). Patients mobilised leucocytes to chambers covering skin windows to the same degree as control subjects, and the mobilisation correlated with the blood leucocyte numbers and serum concentration of alp...

The zinc content of peripheral blood leucocytes has been measured in normal controls and in three groups of patients with liver disease. A significant reduction in leucocyte zinc, but not erythrocyte zinc, was observed in patients with primary biliary cirrhosis, alcoholic cirrhosis, and active chronic hepatitis. It is suggested that the nucleated tissues of some patients with liver disease are ...

Twenty-five patients with congenital cyanotic heart disease were studied. Skiagrams of the skull (posteroanterior and lateral views), pelvis and lumbar spine (posteroanterior and lateral views), upper limb (posteroanterior view only), and x-ray of ankle joint including lower ends of tibia and fibula (posteroanterior and lateral views) were taken. Haemoglobin, packed cell volume, total leucocyte...

The leucocyte data on four malnourished children who died suddenly when high-energy feeding was started were retrospectively analysed. The pretreatment rate constant for sodium efflux in leucocytes was higher and the intracellular sodium concentration lower in this group than in 13 malnourished children who recovered uneventfully with feeding. Two other children with unusual leucocyte electroly...