Pigmented Bowen's disease is rare, though more prevalent in men. It presents as a well-delineated plaque in areas unexposed to sun. There are reports of association with seborrheic keratosis, solar lentigo or exuberant pigmentation of genital and intertriginous regions. A specific dermoscopy finding is the presence of brown or gray dots in regular arrangement and coiled or dotted vessels. Thus,...

Imiquimod activates the immune system when applied to a local area. We report a patient with a history of well-controlled myasthenia gravis who was prescribed imiquimod for lentigo maligna. Treatment was halted after 2 weeks when the patient reported itching and irritating sensations in his throat, consistent with previous myasthenia exacerbations. The symptoms improved once imiquimod use was d...

Sir, Melanocytes are the skin cells most vulnerable to cold; they can be destroyed by temperatures of ± 4 to ± 73C (1). Lower tissue temperatures or repeated freeze ± thaw applications lead to skin necrosis (2). Selective destruction of melanocytic lesions by skin freezing can therefore be achieved without epithelial loss or skin necrosis if certain technical requirements are taken into account...

L entigo maligna (LM) is an in situ lesion with a 2% to 50% risk of progression to LM melanoma. Currently, surgery or radiotherapy is usually recommended as the primary treatment for LM. In the literature, the recurrence rates reported for radiotherapy range from 0% to 19%, with a mean recurrence rate of approximately 7%; in addition, radiotherapy carries the risk of causing chronic radiodermat...

Figure 3 Atypical acquired melanosis, shown by clusters ofabnormal melanocytes in the epithelium, migrating awayfrom the basement membrane. Squamous metaplasia ofthe epithelium, with loss ofgoblet cells, is also seen. Haematoxylin and eosin. Magnifcation x300. We present an unusual case in which conjunctival melanoma was preceded by excision of a lentigo maligna melanoma ofthe ipsilateral lower...

Patients sometimes experience complex diagnostic and treatment procedures. During these processes, they need to rely on the information provided by care providers. In particular, if would like play an active role in shared decision-making process, it is important that this accessible, complete understandable. A patient with Lentigo Maligna nose has been followed during process of diagnosis, tre...

Primary cutaneous melanomas are usually divided into three separate clinicopathologic groups: lentigo maligna melanoma (LMM), superficial spreading melanoma. (SSM), and nodular melanoma (NM). Acral lentiginous melanoma has been described as the fourth distinct subtype to denote those melanomas that arise on volar and subungual skin. This entity is said to have a radial growth phase histological...

Dermoscopy has its usefulness well established in the diagnostic evaluation of melanocytic lesions. Recently, however, it has also shown to be an important tool in monitoring therapeutic response to various dermatoses. We report the case of an elderly patient diagnosed with lentigo maligna of difficult surgical management, which we have chosen to treat with topical imiquimod. The dermoscopic mo...