The human arylamine N-acetyltransferases NAT1 and NAT2 are important xenobiotic-metabolizing enzymes involved in the detoxification and metabolic activation of numerous drugs and chemicals. NAT activity depends on genetic polymorphisms and on environmental factors. It has been shown that low NAT-acetylation activity could increase the risk of age-dependent cataract, suggesting that NAT detoxifi...

The recommendation from the International Commission on Radiological Protection that the occupational equivalent dose limit for the lens of the eye should be reduced to 20 mSv year(-1), averaged over 5 years with no year exceeding 50 mSv, has stimulated a discussion on the practicalities of implementation of this revised dose limit, and the most appropriate risk and protection framework to adop...

Cataract is defined as an opacification of the lens resulting in visual impairment. Worldwide, it is the number one cause of blindness and there are currently no strategies to prevent the onset of the disease. Cataract surgery is the most commonly performed elective intervention in industrialized countries. The condition has thus major impact on national and international health care systems. E...

OBJECTIVE To measure surface skin dose from various cone-beam computed tomography (CBCT) scanners using point-dosimeters. MATERIALS & METHODS A head anthropomorphic phantom was used with nanoDOT optically stimulated luminescence (OSL) dosimeters (Landauer Corp., Glenwood, IL) attached to various anatomic landmarks. The phantom was scanned using multiple exposure protocols for craniofacial eva...

PURPOSE We retrospectively reviewed the results of radiotherapy for localized ocular adnexal MALT lymphoma (OAML) to investigate the risk factors of cataract. METHODS Sixty-seven patients with stage IE OAML treated with radiotherapy at Seoul St. Mary's Hospital from 2001 to 2016 were included. Median treatment dose was 30 Gy. Lens protection was done in 52 (76%) patients. Radiation therapy (R...

purpose: to describe the biometric changes and their effect on intraocular lens (iol) power calculation after trabeculectomy and to compare the accuracy of four formulas namely srk/ii, srk/t, holladay and hoffer q for iol power calculation in these patients. methods: thirty-four eyes of 31 glaucoma patients who were scheduled for primary trabeculectomy were enrolled. a non-contact biometry devi...

purpose: to evaluate the safety, efficacy, stability and predictability of posterior chamber collagen copolymer phakic intraocular lens (piol) implantation to correct myopia and myopic astigmatism in keratoconus-affected patients. methods: uncorrected (ucva) and best-corrected (bcva) distance visual acuity, refraction and complications were evaluated in 22 keratoconic eyes of 14 patients who un...

purpose: to compare visual outcomes and surgical complications of three phakic intraocular lenses (piols); artisan, artiflex and the implantable collamer lens (icl) for correction of moderate to high myopia. methods: in this historical cohort study, 112 myopic eyes that were operated between 2005 and 2010 and implanted with one of these three piols were evaluated (artisan 40 eyes, artiflex 36 e...

background: silicon hydrogel bandage contact lenses are used to enhance epithelial healing, control surface-generated pain, and prevent epithelial erosions after refractive surgery. considering the importance of faster reepithelialization in preventing complications of photorefractive keratectomy (prk) and the fact that the features and specifications of these commercially-available lenses are ...