OBJECTIVE To assess risk factors for erysipelas of the leg (cellulitis). DESIGN Case-control study. SETTING 7 hospital centres in France. SUBJECTS 167 patients admitted to hospital for erysipelas of the leg and 294 controls. RESULTS In multivariate analysis, a disruption of the cutaneous barrier (leg ulcer, wound, fissurated toe-web intertrigo, pressure ulcer, or leg dermatosis) (odds r...

A 77-year-old man with a history of surgical resection of malignant melanoma involving the fifth toe of his left foot 14 years ago presented at the Kariya Toyota General Hospital with a 3-month history of skin ulcer at the same site and red nodules on the lower left leg. Malignant melanoma was suspected, and the patient was referred to our department. On examination, a skin ulcer measuring 25 ×...

Introduction: Leg ulcers are a syndrome characterized by loss of tegument that affect the lower extremities usually caused by vascular system dysfunction, representing a high morbidity chronic disease especially among the aged. This study determined the epidemiological characteristics of leg ulcer patients seen at Clinical Hospital Ribeirão Preto from 1991 to 2001, and their main etiologies and...

Leg ulcers are a chronic manifestation of sickle-cell disease (SCD) and are often painful, disabling, and difficult to treat. RGD peptide matrix treatment is a novel therapy designed to provide a topical synthetic extracellular matrix that can act as a temporary substitute for the damaged natural matrix at the ulcer site. In this randomized, placebo-controlled, double-blind, prospective, multic...

Background: Venous ulcers are a major problem for patients with chronic venous disease (CVD) such as varicose veins. Its treatment is very complex and requires great care, such that inappropriate responses to various medical and surgical treatment could change this condition. This report aims to provide clinical experiences of Iranian traditional medicine that ...

Leishmaniases are parasitic diseases occurring in endemic tropical and subtropical areas and caused by protozoa of the genus leishmania, transmitted by a diptera (sand fly). We here report a case of topical cutaneous leishmaniasis discovered in a 15-year old boy with painless ulcer on his left leg, who had been staying in South Africa. Clinical examination showed painless non-itchy ulcer, occur...

Introduction It has been demonstrated that plasma growth factor (PGF) responsible for proliferation of smooth muscle cells and fibroblasts significantly shortens treatment duration. Aim To determine the role of human growth factor in the healing of ulcers due to ischaemic diabetic foot syndrome (DFS) following previous angioplasty of the blood vessels of the lower leg and foot. Material and...