The purpose of this study is to evaluate the intensity modulated radiotherapy (IMRT) with the fixed collimator jaws technique (FJT) for the left breast and regional lymph node. The targeted breast tissue and the lymph nodes, and the normal tissues were contoured for 16 left-sided breast cancer patients previously treated with radiotherapy after lumpectomy. For each patient, treatment plans usin...

Breast augmentation with the use of silicone breast implants is a routine practice for surgeons. implant capsule‑associated squamous cell carcinoma rare and aggressive malignant tumor accounting less than 0,1 % invasive cancer. Currently there no single concept complex therapy such tumors due to low incidence rate. The article describes case 49‑year‑old female patient after surgical treatment l...

PURPOSE For patients with left-sided breast cancers, radiation treatment to the intact breast results in high doses to significant volumes of the heart, increasing the risk of cardiac morbidity, particularly in women with unfavorable cardiac anatomy. We compare helical tomotherapy (TOMO) and inverse planned intensity modulated radiation therapy (IMRT) with three-dimensional conformal radiothera...

BACKGROUND Although adjuvant radiotherapy (RT) following surgery for breast cancer improves overall survival, controversy exists about its long-term adverse impact on cardiovascular health in older survivors. AIM To determine whether incident cardiovascular disease (CVD) is associated with RT and whether tumor laterality modifies this association. METHODS Women aged 65+ years diagnosed with...

BACKGROUND AND PURPOSE Left-sided breast cancer patients pose a difficult clinical challenge when significant heart and contralateral breast irradiation are present, particularly with tangential uniform beams. The aims of the study are: (1) to design and evaluate a simplified intensity-modulated radiotherapy (IMRT) (SI) solution using pre-defined segments, (2) to compare the SI technique with a...

PURPOSE To evaluate cardiac doses in breast cancer patients with stage II/III treated with 4-field radiotherapy based on computed tomography (CT) dose planning. METHODS AND MATERIALS Based on archived CT images, whole heart and cardiac chamber radiation doses were analyzed in 216 (111 left-sided and 105 right-sided) mastectomized or lumpectomized breast cancer patients treated at a single ins...

BACKGROUND Women with breast cancer who are treated with adjuvant radiation have a decreased risk of local recurrence but an increased risk of mortality from ischemic heart disease. Patients with left-sided breast tumors receive a higher dose of radiation to the heart than patients with right-sided tumors. Because radiation techniques have improved over time, we investigated whether the risk of...

Post-mastectomy radiotherapy (PMRT) has been shown to improve disease-free survival and overall survival for locally advanced breast cancer. However, long term survivors may develop life threatening acute and chronic treatment-related toxicities after radiotherapy, like cardiac toxicity and second cancers. The more advanced techniques like volumetric arc therapy (VMAT), and proton therapy have ...