نتایج جستجو برای: leaky gut

تعداد نتایج: 54822  

2016
George Tetz Victor Tetz

Increased intestinal permeability and translocation of gut microbiota from the intestinal lumen to the systemic circulation predispose patients to various diseases and may be one of the main triggers thereof. The role of microbiota in increased intestinal permeability is under intensive investigation. Here, we studied alterations in the host and increased intestinal permeability as a direct eff...

Journal: :Royal Society Open Science 2021

Perceived as environmental-friendly hydraulic structures, leaky barriers used for natural flood management are introduced into rivers, potentially creating migration fish. Using sustainable, local materials to construct wooden across river channels in upper catchments, these aim slow down the flow, reduce peaks and attenuate flow reaching downstream communities. Yet little is known about their ...

Introduction: A neurodevelopmental disorder, autism typically identified with three primary behavioral consequences, such as social impairment, communication problems and limited or stereotypical behavior. Because of its co-morbidity and lack of therapeutic options, autism is a global economic burden. A short chain of fatty acid, propionic acid formed biologically by gut microbiome. Propionic a...

2015
Anton Pallin

Fermentation of foodstuffs has beneficial effects on shelf life, taste and texture and possibly also health of the consumer. Products containing microbes with beneficial health effects for the host are defined as probiotics. One probiotic bacterium, Lactobacillus reuteri, has been shown to exert positive effects on a number of diseases and disorders, including a possible protective role against...

Journal: :PLoS ONE 2007
Sya N. Ukena Anurag Singh Ulrike Dringenberg Regina Engelhardt Ursula Seidler Wiebke Hansen André Bleich Dunja Bruder Anke Franzke Gerhard Rogler Sebastian Suerbaum Jan Buer Florian Gunzer Astrid M. Westendorf

BACKGROUND Probiotics are proposed to positively modulate the intestinal epithelial barrier formed by intestinal epithelial cells (IECs) and intercellular junctions. Disruption of this border alters paracellular permeability and is a key mechanism for the development of enteric infections and inflammatory bowel diseases (IBDs). METHODOLOGY AND PRINCIPAL FINDINGS To study the in vivo effect of...

2015
Andrea Michielan Renata D'Incà

The pathogenesis of inflammatory bowel disease (IBD) is multifactorial with data suggesting the role of a disturbed interaction between the gut and the intestinal microbiota. A defective mucosal barrier may result in increased intestinal permeability which promotes the exposition to luminal content and triggers an immunological response that promotes intestinal inflammation. IBD patients displa...

2012
Phillipp Hartmann Wei-Chung Chen Bernd Schnabl

Alcoholic liver disease (ALD) encompasses hepatic steatosis, which may progress to alcoholic hepatitis, fibrosis, and cirrhosis. It remains a leading cause of morbidity and mortality in the US and worldwide. The severity of liver disease correlates with plasma levels of bacterial products in patients, and experimental ALD depends on the level of gut derived bacterial products in rodents. Since ...

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