Objective: it is well known that low omentin levels and reduced bioavailability of nitric oxide (NO) are outgrowth obesity. Besides, in obese subjects, microvascular dysfunction can be an initial stage cardiovascular diseases. This situation evaluated with skin laser–Doppler flowmetry (LDF).Methods: this study we investigated the effects 12 weeks moderate physical exercise on reactivity plasma ...

The laser Doppler flowmetry (LDF) technique provides the monitoring of microvascular blood flow perfusion. However, LDF monitors based on fiber-optic transducers have the serious drawback of generating TRAnsient Signal High-values (TRASH) in signals. These TRASH correspond to artifacts for clinicians as they prevent interpretations of the signal when they are numerous. Moreover, TRASH exclude t...

To date, the only published reports of bone mineral density (BMD) in MPS IV involve patients with MPS IVA; no reports exist describing BMD for MPS IVB. In this prospective study of BMD in three patients with MPS IVB, BMD was acquired by dual-energy X-ray absorptiometry (DXA) at whole body (WB), lumbar spine (LS), and lateral distal femur (LDF). Functional abilities, ambulatory status, medical h...

BACKGROUND Laser Doppler flowmetry (LDF) can be used to measure cerebral microcirculation in relation to stereotactic deep brain stimulation (DBS) implantations. OBJECTIVE To investigate the microcirculation and total light intensity (TLI) corresponding to tissue grayness in DBS target regions with high-resolution LDF recordings, and to define a resolution which enables detection of small ves...

Our research is related to the employment of photoplethysmography (PPG) and laser Doppler flowmetry (LDF) techniques (measuring the blood volume and flux, respectively) for the peripheral vascular system. We derive the governing equations of the wave dynamics for the case of extremely inhomogeneous parameters. We argue for the conjecture that the blood-vascular system as a wave-conducting mediu...

We analyze the statistics of work generated by a gradient flow to stretch a nonlinear polymer. We obtain the large deviation function (LDF) of the work in the full range of appropriate parameters by combining analytical and numerical tools. The LDF shows two distinct asymptotes: "near tails" are linear in work and dominated by coiled polymer configurations, while "far tails" are quadratic in wo...

The exact large deviation function (ldf) for the fluctuations of the energy density field is computed for a chain of Ising (or more generally Potts) spins driven by a zero-temperature (dissipative) Glauber dynamics and sustained in a non trivial stationary regime by an arbitrary energy injection mechanism at the boundary of the system. It is found that this ldf is independent of the dynamical d...

The local dependence function (LDF) describes changes in the correlation structure of continuous bivariate random variables along their range. Bivariate density functions with Beta marginals can be used to model jointly a wide variety of data with bounded outcomes in the (0,1) range, e.g. proportions. In this paper we obtain expressions for the LDF of bivariate densities constructed using three...

BACKGROUND Endothelial dysfunction precedes atherosclerosis. Vasodilation induced by acetylcholine (ACh) is a specific test of endothelial function. Reproducibility of laser techniques such as laser-Doppler-flowmetry (LDF) and Laser-speckle-contrast-imaging (LSCI) to detect ACh vasodilation is debated and results expressions lack standardization. We aimed to study at a 7-day interval (i) the in...