late-onset alzheimer's disease (ad), a genetically heterogeneous neurodegenerative disorder, is the most common form of dementia in people over 65 years old. the role of vitamin d in neuropsychiatric and neurodegenerative disorders such as ad has been supported by epidemiologic investigations and animal models, as well. we examined the association of the vitamin d receptor (vdr) gene polymorphi...

late-onset alzheimer's disease (load) is a neurodegenerative disorder and the most common form of dementia affecting people over 65 years old. alzheimer’s disease is a complex disease with multi-factorial etiology. inflammation has been approved to have an important role in the pathogenesis of alzheimer’s disease (ad). tnf-a is a main pro-inflammatory cytokine that plays an essential role in in...

oxidation of low density lipoprotein (ldl) particles plays a key role in the etiology of atherosclerosis and coronary artery disease (cad). oxidative stress enhances the likelihood of ldl oxidation and atherosclerotic plaque development. paraoxonase (poni) is an enzyme associated with hdl that metabolizes organophosphates and has antioxidant activity. in order to investigate the relationship be...