PURPOSE This study was designed to evaluate the clinical characteristics of childhood diabetes mellitus (DM) according to its classification as well as the clinical course of latent autoimmune diabetes (LAD) that initially showed noninsulin dependence despite autoantibody positivity. METHODS A total of 91 subjects diagnosed between 2001 and 2015 were enrolled in the study. They were classifie...

The distribution of atherosclerotic plaque burden in the human coronary arteries is not uniform. Plaques are located mostly in the left anterior descending artery (LAD), then in the right coronary artery (RCA), circumflex branch (LCx) and the left main coronary artery (LM) in a decreasing order of frequency. In the LAD and LCx, plaques tend to cluster within the proximal segment, while in the R...

Long noncoding RNAs (lncRNAs) have been identified as oncogenes or tumor suppressors that are involved in tumorigenesis and chemotherapy drug resistance. Maternally expressed gene 3 (MEG3) is an imprinted gene located at 14q32 that encodes an lncRNA, and decreased MEG3 expression plays an important role in multiple cancers. However, its biological role in the development of the chemoresistance ...

A 68-year-old man underwent successful 3-vessel coronary artery bypass grafting (CABG): a left internal mammary artery (LIMA) was anastomosed end to side to a large diagonal branch of the left anterior descending coronary artery (LAD) and was then skipped to the distal LAD; and saphenous vein grafts (SVGs) were anastomosed to the circumflex and right coronary arteries. He returned to his cardio...

The localization algorithm based on the doublethresholding (LAD) method was originally proposed for detecting and localizing narrowband (NB) signals with respect to the search bandwidth. Its weakness is that the localized signal is often split into several parts, especially when the signal-to-noise ratio (SNR) is low. This may lead to the illusion of unoccupied frequencies in the middle of the ...

The large and multiple spontaneous coronary artery dissections of a 54-year-old man Coronary angiography demonstrated spiral dissection of right coronary artery (RCA) and of proximal and second diagonal branch the left descending coronary artery (LAD) (Figs. 1 and 2), and significant obstruction of the proximal segment of LAD. Revascularization was performed with LIMA to LAD and saphenous vein ...

The anomalous origin of the right coronary artery (RCA) from the left anterior descending (LAD) artery is rare. We report a case of single coronary artery with proximal LAD severe stenosis. The RCA originated from an unreported course of conal branch from the LAD. This anomalous RCA also had collaterals from left circumflex. Coronary intervention was successfully carried out on a severe stenosi...

Coronary artery stenoses that limit blood flow below demand are considered critical. In this comparative study we investigated whether the same degree of stenosis in either the proximal third of the right coronary artery (RCA) or the proximal third of the left anterior descending artery (LAD) causes critical flow reduction. Lesions were quantified from 35-mm cinefilms in multiple projections us...

SUMMARY The time intervals defined by the simultaneous recording of an electrocardiogram, phonocardiogram, indirect carotid pulse curve, and apexcardiogram made it possible to compare the left ventricular (LV) dynamics in a group of 33 cases of complete right bundle-branch block with left axis deviation (RBBB-LAD) with two control groups, one consisting of 30 cases of complete right bundle-bran...

Studies in animals have suggested that increases in blood flow result in dilation of large arteries by an endothelium-dependent mechanism. Atherosclerosis can impair endothelium-dependent vasodilation to vasoactive agents. The purpose of this study was to determine whether or not large coronary arteries in humans exhibit dilation with increases in blood flow and to test the hypothesis that this...