INTRODUCTION The turnover of Ringer´s solutions is greatly dependent on the physiological situation, such as the presence of dehydration or anaesthesia. The present study evaluates whether the kinetics is affected by previous infusion of colloid fluid. METHODS Ten male volunteers with a mean age of 22 years underwent three infusion experiments, on separate days and in random order. The experi...

Four pigs initially of 30 kg live weight were surgically prepared with two re-entrant cannulas in the jejunum 1.0 m apart which allowed an isolated loop to be formed through which solutions were perfused. 51Cr-EDTA was used as a marker for measuring net secretion or absorption. A new Ringer solution was made, the ionic content of which resembled more closely that found in the jejunum of pigs gi...

BACKGROUND Spinal anesthesia is an important and commonly used method for surgical anesthetic in operating rooms. However, even with identical drug dosage and administration mode, the extent of drug distribution in vivo is highly variable and difficult to control. Preanesthetic administration of fluids immediately before spinal anesthesia (preload) is normal practice. The choice of fluid type m...

It has been suggested that collecting duct sodium transport was inhibited by extracellular volume expansion. To directly evaluate this possibility, micropuncture of the papillary collecting duct of young rats was performed during hydropenia and Ringer loading. The possibility of heterogeneity of nephron function was evaluated during Ringer and hyperoncotic albumin loading by comparing the deliv...

KAPOPORT, STANLEY I., AND JEANNETTE M. BIDINGER. Eject of stretch on contractility and ionic contents of the sartorius muscle of Rana pipiens. Am. J. Physiol. 226(Z) : 452-457’ 1974.-When sartorius muscles of frogs are soaked in Ringer at room temperature, they gain Na, lose K, and lose contractility with time. These changes are retarded by stretching the muscles to ZO-30Y0 of their rest length...

Guanylin (GN) action on seawater eel intestine was examined under simulated in vivo conditions, where isotonic luminal fluid has low NaCl and high MgSO4 (MgSO4 Ringer). In Ussing chamber, MgSO4 Ringer induced serosa-negative potential difference (PD) even after bumetanide treatment, which is due to the higher paracellular Na(+) permeability over Cl(-), as confirmed by the replacement by MgCl2 (...

This experimental work was performed on 4 rabbits to demonstrate that administrations of oxygenated Ringer's lactate through the central venous infusion could be used as a means of oxygenation. The oxygen tensions of Ringer's lactate were determined upon changing the amount of oxygen being bubbled and the solutions with the mean PO2 and pH of 575.5 mmHg and 6.34 were used in this study. We did ...

KAPOPORT, STANLEY I., AND JEANNETTE M. BIDINGER. Eject of stretch on contractility and ionic contents of the sartorius muscle of Rana pipiens. Am. J. Physiol. 226(Z) : 452-457’ 1974.-When sartorius muscles of frogs are soaked in Ringer at room temperature, they gain Na, lose K, and lose contractility with time. These changes are retarded by stretching the muscles to ZO-30Y0 of their rest length...