The lacquer scabbard of a bronze sword dating from the Warring States (476–221 BCE) and excavated Ba tomb Lijiaba site (Chongqing, southwest China) was characterized by multidisciplinary approach including microscopy, scanning electron microscopy-energy dispersive X-ray spectrometry (SEM-EDS), Raman spectroscopy pyrolysis–gas chromatography/mass (Py-GC/MS). Pyrolysis-comprehensive two-dimension...

UNLABELLED PURPOSE. To identify the risk factors for development of myopic choroidal neovascularization (mCNV), a major cause of visual impairment. METHODS. Enrolled in the study were 23 consecutive patients with bilateral high myopia (axial length, > or =26.5 mm or refractive error, < or =8 D) and unilateral newly developed mCNV who presented to the Myopia Clinic, Osaka University Hospital. Sp...

The flavonoid fisetin (3, 3, 4, 7-tetrahydroxyflavone) is the main component of lacquer and is found in strawberries, apples, and grapes. The lacquer, lac tree extract, has been used as Chinese medicine in Asia for thousands of years. Several recent studies have demonstrated that the flavonoid has anticancer effects against several cancer types. Our preliminary data have indicated that fisetin ...

We developed a novel model of onychomycosis in which we observed fungi in the deep layer of the nail, and we used the model to evaluate the efficacy of two topical antifungal drugs. To establish an experimental, in vivo model of onychomycosis, we applied Trichophyton mentagrophytes TIMM2789 to the nails of the hind limbs of rabbits that underwent steroid treatment. The nails were taken from the...

BACKGROUND Many onychomycosis treatments have not been directly compared in head-to-head clinical trials. OBJECTIVE To determine the relative efficacy of onychomycosis treatments using network meta-analysis (NMA). METHODS We conducted a systematic review and NMA of mycological cure rates. RESULTS Nineteen trials were included in the network. Terbinafine 250 mg was significantly superior t...

onychomycosis constitutes the most common fungal infection of nail affecting finger and toe nails as well. antifungals found to be effective in the treatment of onychomycosis. however, transport of oral antifungal agents exhibits more toxicity and requires longer treatment period. medicated nail lacquers proved to cause lesser toxicity and required shorter treatment period. it provides not only...