Heart failure is the leading cause of mortality in patients with transfusional iron (Fe) overload in which myocardial iron uptake ensues via a transferrin-independent process. We examined the ability of L-type Ca2+ channel modifiers to alter Fe2+ uptake by isolated rat hearts and ventricular myocytes. Perfusion of rat hearts with 100 nmol/L 59Fe2+ and 5 mmol/L ascorbate resulted in specific 59F...

The absorption, metabolism, and clearance of progesterone from the peripheral circulation were investigated in five postmenopausal women after oral administration of 100 mg daily for five consecutive days. Maximal plasma concentrations of progesterone were observed within four hours after ingestion of the last dose, when the range (22.11-34.18 nmol/l; 696-1077 ng/100 ml) was comparable with tha...

Using electron energy loss spectroscopy, we have probed the spin waves of fcc(100) cobalt after capping with 1–3 atom layers of pseudomorphic nickel or up to 12 atom layers of copper. The intensity decay of the spin wave signal is quantitatively described by the mean-free path of the incident and the scattered electron within the capping layer. The observed spin waves are therefore localized at...

Author’s E-mail: [email protected] Tel:+964-7702660991 In an attempt to combine the favourite properties of hard gelatine capsules with the protective and controlled release properties of enteric coating to get an appropriately and acceptably formulated enteric coated hard gelatine capsules with pH dependent drug release characteristic. Two hard gelatine capsule sizes were selected i.e. siz...

We have shown previously that tri-iodothyronine (T3)-induced sex hormone-binding globulin (SHBG) secretion by the human hepatoblastoma cell line, HepG2, can be modulated by retinoids. We have now used this model to study a range of other compounds that are known to influence T3 responsiveness in various cell systems. HepG2 cells were incubated for 4 days in serum-free medium containing T3, toge...

Field trials with Ficus benjamina L.were conducted at the experimental farm of Faculty of Agriculture, University Azad Jiroft in 2012 growth seasons. The aim of this work is to study the effect of foliar application with gibberellic acid (GA3) and benzyladenine (BA) at 0, 100 and 200 mg.L-1 on the vegetative growth and Photosynthetic pigments of Ficus benjamin...

field trials with spathiphyllum wallisii regel were conducted at the experimental farm of faculty of agriculture, university azad jiroft in 2012 growth seasons. the aim of this work is to study the effect of foliar application with benzyladenine (ba) at 0, 100, 200 and 400 mg.l-1 and gibberellic acid (ga3) at 0, 100 and 200 mg.l-1 on the vegetative growth constituents of spathiphyllumplants. mo...

Objective: Does carbachol (CCh) require NO/cGMP for inhibition of L-type calcium current (I ) when either adenylyl cyclase Ca(L) activation or phosphodiesterase suppression is used to raise cAMP? Methods: The effects of the NO donor SIN-1 (3-morpholinosydnonimine), CCh and atrial natriuretic peptide (ANP) were evaluated when I had been stimulated by isoproterenol (ISO) or Ca(L) 3-isobutyl-1-met...