The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under ...

Expert identification has become an important information retrieval task. We present and investigate a number of approaches for identifying an expert. Different approaches are based on exploiting the structure of documents in the knowledge base. Furthermore, our system highlights the integration of database technology with information retrieval (DB+IR).

Knowledge bases (KB) provide support for real-world decision making by exposing data in a structured format. However, constructing knowledge bases requires gathering data from many heterogeneous sources. Manual efforts for this task are accurate, but lack scalability, and automated approaches provide good coverage, but are not reliable enough for realworld decision makers to trust. These two ap...

To effectively manage the heterogeneous and discrete knowledge of bridge maintenance domain, this study adopts graph technology to build a base maintenance, called (BMKG). The BMKG uses an ontology as organization representation framework database storage tool. facilitate construction BMKG, hybrid method combining top-down approach bottom-up is proposed. Firstly, domain (BMDO) coded with Protég...

By E. Hassan February 2002 Abstract This paper examines the knowledge structure of the field of space communications using bibliometric mapping techniques based on textual analysis. A new approach with the aiming of visualizing simultaneously the configuration of its scientific and technological knowledge bases is presented. The bibliometric map revealed weak cognitive interactions between scie...

miRò is a web-based knowledge base that provides users with miRNA-phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows no...

In this paper we present a framework of retrospective reasoning to deal with the belief revision problem in knowledge systems. First, a rst-order knowledge base is represented by a set of formulas in a rst order epistemic belief language that contains objective formulas as well as belief formulas. Secondly, we deene the revision operation by applying a form of prioritized circumscription to thi...

Information processing environments have been rapidly changing in many elds: not only changes of network environments and hardware systems, but also enhanced requirements of application systems, database systems, and knowledge-base systems. It is necessary to reconsider how to construct information systems in new environments. For example, in databases, there are many di culties to cope with ad...

The value of a corporate information system such as an experience base tends to degrade with time. To keep the value of such a system, maintenance is an essential. Maintenance should not simply happen ad-hoc but systematically and based on specific maintenance knowledge. As a jump-start for maintenance, maintenance knowledge should be available right from the start of continuous operation. This...