1 Pediatric Gastroenterologist, MSc in Clinical Nutrition, Gastronutriped, Director of Graduate Pediatric Gastroenterology University Forest Officer. Bogotá, Colombia [email protected] 2 Clinical Nutritionist, MSc in Clinical Nutrition, Graduate Assistant Professor of Pediatrics and Pediatric Gastroenterology. Universidad El Bosque in Bogotá, Colombia 3 Pediatrician, Fellow of Pedi...

Interleukin-5 (IL-5) is known to play a major role in the growth, differentiation, recruitment, and activation of eosinophils. The authors review the efficacy and safety of two IL-5-targeting agents used in the treatment of eosinophilic asthma.

Primary malignant melanoma of the esophagus (PMME) accounts for 0.1–0.2% of all malignant disease of the esophagus. Ninety-five percent of all melanomas are found in the derma, and only 0.5% are localized in the esophagus (Bisceglia et al. 2011). The prognosis of PMME is unfavorable because most patients are in the advanced stage at diagnosis and rapidly develop lymph node and distant metastase...

1. Kimura K, Suzuki S, Wachino J et al. First molecular characterization of group B streptococci with reduced penicillin susceptibility. Antimicrob Agents Chemother 2008; 52: 2890–7. 2. Nagano N, Nagano Y, Kimura K et al. Genetic heterogeneity in pbp genes among clinically isolated group B streptococci with reduced penicillin susceptibility. Antimicrob Agents Chemother 2008; 52: 4258–67. 3. Jon...

Mepolizumab (Nucala) for severe eosinophilic asthma.

Yasuo Honma, Yuko Yoshii, Yumiko Watanabe, Nobuki Aoki, Takako Komiya, Masaaki Iwaki, Hiroyuki Arai, Yoshichika Arakawa, Motohide Takahashi*, and Hirokazu Kimura Shinrakuen Hospital, Niigata 950-2087; Department of Bacteriology II and Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo 208-0011; and Department of Geriatrics and Gerontology, Institute of Deve...

IN April 1961 it became apparent that an increasing number of patients was attending the out-patients department of the Birmingham and Midland Eye Hospital with a follicular conjunctivitis, and an associated pre-auricular adenitis, which often proceeded to a keratitis. This was soon recognized as an outbreak of epidemic keratoconjunctivitis and therefore precautionary measures were immediately ...