The anticancer agent saintopin induces DNA cleavage mediated by both topoisomerase (topo) I and topo II in vitro through stabilization of the reversible enzyme-DNA cleavable complex. We established saintopinresistant cell lines (KB/STP-1 and KB/STP-2) from human epidermoid cancer KB cells by stepwise exposure to increasing doses of the drug. KB/STP-1 and KB/STP-2 cells showed 12and 44-fold incr...

The anticancer agent saintopin induces DNA cleavage mediated by both topoisomerase (topo) I and topo II in vitro through stabilization of the reversible enzyme-DNA cleavable complex. We established saintopin-resistant cell lines (KB/STP-1 and KB/STP-2) from human epidermoid cancer KB cells by stepwise exposure to increasing doses of the drug. KB/STP-1 and KB/STP-2 cells showed 12- and 44-fold i...

The anticancer agent saintopin induces DNA cleavage mediated by both topoisomerase (topo) I and topo II in vitro through stabilization of the reversible enzyme-DNA cleavable complex. We established saintopinresistant cell lines (KB/STP-1 and KB/STP-2) from human epidermoid cancer KB cells by stepwise exposure to increasing doses of the drug. KB/STP-1 and KB/STP-2 cells showed 12and 44-fold incr...

Kontrasepsi hormonal merupakan salah satu metode kontrasepsi yang paling eefektif dan reversible untuk mencegah terjadinya konsepsi. Metode dibagi menjadi 3 yaitu: pil, suntik, implant. memiliki efek samping yaitu gangguan haid depresi, keputihan, jerawat, satunya adalah perubahan berat badan,(Rahayu Wijanarko, 2017). Tujuan penelitian ini mengetahui hubungan lama penggunaan KB terhadap badan p...

Primož Rebernik Ribič, Benedikt Rösner, David Gauthier, Enrico Allaria, Florian Döring, Laura Foglia, Luca Giannessi, Nicola Mahne, Michele Manfredda, Claudio Masciovecchio, Riccardo Mincigrucci, Najmeh Mirian, Emiliano Principi, Eléonore Roussel, Alberto Simoncig, Simone Spampinati, Christian David, and Giovanni De Ninno Elettra-Sincrotrone Trieste, Strada Statale 14-km 163,5, 34149 Basovizza,...

a Laboratoire de Mathématiques Appliquées aux Systèmes, École Centrale Paris, 92290 Châtenay-Malabry, France b School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi-110067, India c Department of Biomedical Engineering and Computational Science, Aalto University School of Science, P.O. Box 12200, FI-00076 AALTO, Espoo, Finland d Condensed Matter Physics Divisio...

Roman Martoňák,1,* Davide Ceresoli,2 Tomoko Kagayama,3 Yusuke Matsuda,3 Yuh Yamada,4 and Erio Tosatti5,6 1Department of Experimental Physics, Comenius University, Mlynská Dolina F2, 842 48 Bratislava, Slovakia 2CNR Institute of Molecular Science and Technology (ISTM), via Golgi 19, 20133 Milan, Italy 3KYOKUGEN, Graduate School of Engineering Science, Osaka University, Machikaneyamacho 1-3, Toyo...

Giacomo Livan, ∗ Jun-ichi Inoue, † and Enrico Scalas 4, ‡ Abdus Salam International Centre for Theoretical Physics, Strada Costiera 11, 34151 Trieste, Italy Graduate School of Information Science and Technology, Hokkaido University, N14-W9, Kita-ku, Sapporo 060-0814, Japan Dipartimento di Scienze e Innovazione Tecnologica, Laboratorio sui Sistemi Complessi, Università del Piemonte Orientale “Am...

Amine Ahriche, 2, ∗ Salah Nasri, 4, † and Rachik Soualah ‡ Department of Physics, University of Jijel, PB 98 Ouled Aissa, DZ-18000 Jijel, Algeria. The Abdus Salam International Centre for Theoretical Physics, Strada Costiera 11, I-34014, Trieste, Italy. Physics Department, UAE University, POB 17551, Al Ain, United Arab Emirates. Laboratoire de Physique Theorique, ES-SENIA University, DZ-31000 O...

We give sound and complete analytic tableau systems for the propositional bimodal logics KB, KB C , KB 5, and KB 5C . These logics have two universal modal operators K and B , where K stands for knowing and B stands for believing. The logic KB is a combination of the modal logic S5 (for K ) and KD45 (for B ) with the interaction axioms I : Kφ → Bφ and C : Bφ → K Bφ. The logics KB C , KB 5, KB 5...