Macrophages play an important role in the acute tissue inflammatory response through the release of cytokines and growth factors in response to stimuli such as lipopolysaccharide (LPS). Macrophage inflammatory effector functions are also influenced by interactions with the extracellular matrix (ECM). Such macrophage-ECM interactions may be important in regulating chronic inflammatory responses....

Glucocorticoids are potent antiinflammatory drugs. They inhibit the expression of proinflammatory cytokines and adhesion molecules. It has recently been proposed that the underlying basis to such inhibition is the induction of the protein I kappa B, which inhibits the transcription factor NF-kappa B. The latter is a key activator of the genes encoding cytokines and adhesion molecules. The prese...

The minimal region of the human tumor necrosis factor alpha (TNF-alpha) gene promoter necessary for its transcriptional induction by phorbol esters (PMA) in human T and B lymphocyte cell lines has been localized between -52 and +89 nucleotides (nt) relative to the gene's transcriptional start site. Comparison of these sequences to those required to mediate virus or lipopolysaccharide (LPS) indu...

conclusions by using the normal angle kappa determined in this study, pseudodeviations can be identified more precisely in those who might undergo keratorefractive surgery. results a total of 977 healthy participants who aged 18 to 45 years were included consecutively. the study population consisted of 614 females and 363 males. the average angle kappa was 5.00º ± 1.36º at 240.21º ± 97.17º in m...

We construct explicit examples of half-sided modular inclusions ${\mathcal N}\subset{\mathcal M}$ von Neumann algebras with trivial relative commutants. After stating a general criterion for triviality the commutant in terms an algebra localized at infinity, we consider second quantization inclusion large and one-parameter family N}_\kappa\subset{\mathcal M}_\kappa$, $\kappa\geq0$, such that N}...

In this study, Kappa number prediction and diagnosis in continuous Downflow Lo-Solids cooking application is investigated. Gustafson’s Kappa number model is applied for the prediction of the blowline Kappa number. New cooking temperature set point is solved iteratively based on the difference between the predicted and target blow-line kappa numbers. The main active variables for the Kappa numbe...

OBJECTIVE To evaluate involvement of the transcription factor nuclear factor kappa B (NF-kappa B) in the increased expression of cyclooxygenase-2 (COX-2) stimulated by interleukin-1 beta (IL-1 beta) in primary rheumatoid synoviocytes. METHODS We treated early-passage rheumatoid synoviocytes with IL-1 beta and examined the time course of NF-kappa B translocation to the nucleus by Western blot ...

The rational meromorphic functions on $\mathbb{C}\backslash\mathbb{R}$ are studied. We consider the some classes of one, as generalized Nevanlinna $\mathbf{N}_{\kappa}$ and Stieltjes $\mathbf{N}_{\kappa}^{k}$ classes. By Euclidean algorithm, we can find indices $\kappa$ $k$, i.e. determine which class function belongs to $\mathbf{N}_{\kappa}^{k}$.

Cohen’s kappa coefficient has become a standard method for measuring the degree of agreement between two raters. Confidence intervals for kappa and weighted kappa based on its asymptotic variance are available in the SAS system through the FREQ procedure. However, this variance can become unreliable as sample size decreases or as kappa approaches unity. This paper presents a SAS macro for calcu...