نتایج جستجو برای: juvenile glaucoma
تعداد نتایج: 71837 فیلتر نتایج به سال:
The aim of this study was to evaluate the efficacy of diode laser cyclophotocoagulation in paediatric patients with refractory glaucoma and to assess complications associated with this method. The study included 69 eyes in 53 children with uncontrolled refractory glaucoma who underwent diode laser cyclophotocoagulation (cyclodiode) treatment. The mean age of this group was 6.1 years (range, 0.9...
PURPOSE The aim of this study was to characterize a representative sample of the Peruvian population suffering open-angle glaucoma (OAG) with respect to the myocilin gene (MYOC) mutations, glaucoma phenotype, and ancestry for future glaucoma risk assessment. METHODS DNA samples from 414 unrelated Peruvian subjects, including 205 open-angle glaucoma cases (10 juvenile glaucoma [JOAG], 19 norma...
Glaucoma, the leading cause of irreversible blindness world wide, affecting about 70 million people, 2 is characterised by progressive loss of optic nerve axons and visual field damage. As the condition is insidious, the diagnosis is often missed and the disease detected only later when patients have severe and irreversible visual impairment. Adult primary open angle glaucoma (POAG) is a major ...
Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...
Introduction: Glaucoma is one of the leading causes of blindness throughout the world. Some studies have suggested a relationship between glaucoma and sensorineural hearing loss, while others have found no evidence of an association. We performed a study to determine whether there is a significant difference in hearing of patients with glaucoma and a match control population. Methods: In this...
Background and Aim: Glaucoma, with an increasing pressure inside the eye, is one of the causes of blindness worldwide. The only glaucoma treatment is regular eye examination and control of intraocular pressure (IOP). The centralized information obtained from these examinations is an essential prerequisite for providing optimal healthcare which is possible by creating electronic records. Minimum...
The GLC1A locus for autosomal dominant juvenile and middle age onset primary open angle glaucoma (OAG) has been mapped to chromosome 1q21-q31. OAG, however, is a heterogeneous disease. We tested linkage of OAG and ocular hypertension (OHT), a major risk factor for OAG, to GLC1A in eight French families with multiple cases of juvenile and middle age onset OAG. There was strong evidence of geneti...
Background: Immune reactions have been reported to be involved in the destruction of retinal ganglion cells (RGCs) in glaucoma. Objective: To investigate the role of major histocompatibility complex class I-related chain A and B (MICA and MICB) molecules in the pathogenesis of glaucoma. Methods: Aqueous humor and serum samples from 15 glaucoma patients and 45 patients with cataract, undergoing ...
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