Imbalance in oxidant and antioxidant status is one of the commonly observed phenomenon in several pathological conditions including cancer. Also, defect in detoxification cascade leads to accumulation of toxic metabolites, which cause mutation in DNA and leads to neoplastic transformation. Aim of the present study is to focus the chemopreventive potential of Adhatoda vasica leaves during DMBA i...

This study determined the nutritive value of Indigoferra gerardiana, Marisine affricana, Impashion bicolor and Adhatoda vesica shrubs for ruminants. Chemical analysis revealed that dry matter (DM) content varied from 22.2% (Dodonia viscosa) to 33.6% (Debregeasia salicifolia). Maximum crude protein (19.8%) was observed for Anisomoles indica, while, neutral detergent fiber was greater (67%) in Do...

Liver diseases such as jaundice, cirrhosis etc. are very common worldwide and traditional medicine are proving to be useless or less effective against them. Therefore workers are trying to find out alternate medicine or formulations to combat these diseases. In the present study hepatoprotective activity of aqueous extract of Adhatoda vasica and Vitex negundo on total protein, bilirubin, aspart...

The in vitro antibacterial activities of 29 traditional medicinal plants used in respiratory ailments were assessed on multidrug resistant Gram-positive and Gram-negative bacteria isolated from the sore throat patients and two reference strains. The methanolic, n-hexane, and aqueous extracts were screened by the agar well diffusion assay. Bioactive fractions of effective extracts were identifie...

BACKGROUND Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Aim. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. METHODS The experimental animals were randomly grouped into fi...

In studying the antimicrobial activity of Vasaka, it has been found that Vasaka leaf extract is a broad spectrum antimicrobial agent and microbiostatic. When plates inoculated with microorganisms were grown in presence of Vasaka, no zone of inhibition was obtained. The organisms have grown resistance against Vasaka. The ethanolic extract of Vasaka have no direct effect on microbes like S. mutan...

Vasicine (1) was isolated from the ethanolic extract of Adhatoda vasica Nees (Acanthaceae) and the structure was confirmed using spectroscopic techniques. Acetylcholine esterase, trypsin, DPPH inhibition potential and FRAP assay were carried out using in vitro models. The results showed 38.4 ± 1.2% and 37.4 ± 1.1% activity in acetylcholine and trypsin inhibition assays respectively. The compoun...

Cough is the most common symptom of respiratory diseases. When cough becomes serious, opioids are effective, but they have side effects like sedation, constipation. Therefore, there is a need to have effective antitussive agent which do not have respiratory depressant activity. The present study was carried out to evaluate antitussive activity of Glycyrrhiza glabra and Adhatoda vasica using a c...