AIMS AND BACKGROUND Ezrin is a membrane-cytoskeleton linker protein involved in regulation of the growth and metastatic behavior of cancer cells. Metastatic tumor antigen (MTA) is a potential metastasis-associated protein. The objective of this study was to evaluate the expression of ezrin and MTA and their correlation with clinicopathological features in osteosarcomas of the jaw. METHODS We ...

ABSTRACT Introduction: Denosumab is a human monoclonal antibody that binds to the receptor activator of nuclear factor kB (RANKL), it used in treatment Osteoporosis. The Giant Cell Tumor (GCT) and Aneurysmal Bone Cyst (ABC) use same RANKL, for this reason drug began be its treatment. There consensus on use, dose-time 12-month duration GCT. Not so ABC. In unresectable, disabling or recurrent tum...

Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, characterized histologically by the formation of ductlike structures with amyloid-like deposits. Histogenesis of AOT is still uncertain and it is often considered as a hamartomatous lesion rather than a true neoplasm. AOT has a benign behavior and conservative surgical enucleation or curettage is sufficient. We repo...

conclusions our data provided information on the prevalence and types of intraosseous lesions among an iranian population. this study provided baseline information to help in designing and programming procedures in health care centers in every community so that preventive therapeutic measures can be adopted. patients and methods this cross-sectional descriptive analytical study was carried out ...

Introduction: Brown tumor or lesions resembling giant cell tumor is a rare sequel of hyperparathyroidism and occasionally affect jaw bones. Brown tumor is three times more common in women as compared to men. Mandible is more frequently involved than maxilla. Parathyroidectomy to control HPT is the treatment of choice for brown tumor. Case report: This paper describes a rare case report of brown...

Previously1), we have determined the various jaw movements of rabbits that can be evoked by electrical stimulation of the cortical jaw motor region. Jaw movement induced by stimulation of the neocortical jaw motor region was predominant in a jaw opening direction whereas that following stimulation of the amygdala was predominant in a jaw closing direction. Additionally, these two brain regions ...