نتایج جستجو برای: ivt mrna
تعداد نتایج: 153383 فیلتر نتایج به سال:
Objective: To compare the effect of intravitreal triamcinolone (IVT) alone with combined intravitreal triamcinolone (IVT) and intravitreal bevacizumab (IVB) on central macular thickness (CMT) in patients of diabetic macular edema (DME). Study Design: Randomized control trial. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Jun 2013 to Dec 2013. Material and Methods: Eighty...
BACKGROUND AND PURPOSE Cerebral ischemic events are highly prevalent and associated with high rates of death and disability in patients with infective endocarditis (IE). However, the role of thrombolysis in these patients remains unclear. We sought to determine the rates and outcomes of acute ischemic stroke patients with IE treated with intravenous thrombolysis (IVT). METHODS We determined t...
BACKGROUND We explored the safety of intravenous thrombolysis (IVT) or intra-arterial treatment (IAT) in patients with ischemic stroke on non-vitamin K antagonist oral anticoagulants (NOACs, last intake <48 hours) in comparison with patients (1) taking vitamin K antagonists (VKAs) or (2) without previous anticoagulation (no-OAC). METHODS AND RESULTS This is a multicenter cohort pilot study. P...
We have investigated the reactivity to two human histocompatibility leukocyte antigen (HLA) A11-restricted cytotoxic T lymphocyte (CTL) epitopes derived from amino acids 416-424 (IVTDFSVIK, designated IVT) and 399-408 (AVFDRKSVAK, designated AVF) of the Epstein-Barr virus (EBV) nuclear antigen (EBNA) 4. A strong predominance of CTL clones specific for the IVT epitope was demonstrated in polyclo...
There is a growing recognition of importance of sex in stroke outcome. More women are affected by stroke because of their longer life expectancy and have a worse functional outcome and a lower quality of life after stroke compared with men. In patients with acute stroke, previous research has also shown sex to affect outcome after intravenous thrombolysis (IVT) treatment; although outcome was s...
BACKGROUND AND PURPOSE Little is known on long-term follow-up after thrombolysis in ischemic stroke patients because the majority of studies evaluated outcome at 3 to 12 months. We aimed to assess 5-year outcome after intravenous thrombolysis (IVT). METHODS Cohort study based on the prospective registry of all consecutive ischemic stroke patients submitted to IVT in our Stroke Unit. Five-year...
PURPOSE To compare the results of intravitreal bevacizumab (IVB) injection alone or in combination with intravitreal triamcinolone acetonide (IVT) versus macular laser photocoagulation (MPC) as a primary treatment of diabetic macular edema (DME). DESIGN Randomized 3-arm clinical trial. PARTICIPANTS A total of 150 eyes of 129 patients with clinically significant DME and no previous treatment...
BACKGROUND Cardiac complications are common in familial amyloidotic polyneuropathy (FAP), in which heart rate variability (HRV) is reduced. Although autonomic disturbances are well-established, mechanisms for reduced HRV, their relationship with left ventricular (LV) function in FAP are not well understood. METHODS Twenty-nine FAP patients and 29 healthy controls were studied using Doppler ec...
BACKGROUND AND PURPOSE Recanalization status after intravenous thrombolysis (IVT) in patients with ischemic stroke is a reference point to proceed with a rescue reperfusion intervention, although early neurological improvement (NI) may preclude endovascular procedures. We aimed to evaluate the importance of restoration of blood flow at the arterial occlusion site in subgroups of patients with s...
PURPOSE. A marked cellular infiltrate has been observed when endotoxin (lipopolysaccharide [LPS]) is injected into the mouse eye, but systemically injected LPS does not produce a comparable effect. Several hypotheses were tested to reconcile this discordance. METHODS. BALB/c mice were injected intravitreally (ivt) or intraperitoneally (ip) with Escherichia coli LPS. Uveitis was assessed by trad...
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