BACKGROUND Currently, there is no agreement on the optimal urinary derived human chorionic gonadotropin (u-hCG) dose requirement for initiating final oocyte maturation prior to oocyte collection in in vitro fertilization (IVF), but doses that range from 2500- 15000 IU have been used. We intended to determine whether low dose u-hCG was effective for oocyte maturation in IVF/intracytoplasmic sper...

OBJECTIVE The aims of this study were to evaluate the effect of anticardiolipin antibody (aCL) and lupus anticoagulant (LA) on the outcome of the in vitro ferlitization (IVF) cycles and to determine the prevalence of these antibodies in infertile women seeking IVF in Jamaica. METHODS A retrospective cohort study was performed to determine if screening patients for aCL and LA had any significa...

BACKGROUND Only 25% of IVF transfer cycles lead to a clinical pregnancy, calling for continued technical progress but also more in depth analysis of patients' individual characteristics. The interleukin-1 (IL-1) system and matrix metalloproteinases (MMPs) are strongly implicated in embryo implantation. The genes coding for IL-1Ra (gene symbol IL-1RN), IL-1beta, MMP2 and MMP9 bear functional pol...

OBJECTIVE To determine the relationship between sperm chromatin structure assay (SCSA) parameters (DNA fragmentation index [DFI] and high DNA stainability [HDS]), and conventional IVF and IVF/intracytoplasmic sperm injection (ICSI) outcomes. DESIGN Retrospective review and prospective study. SETTING Private IVF clinic. PATIENT(S) Two hundred forty-nine couples undergoing first IVF and/or ...

OBJECTIVE To determine a successful method of selecting patients for natural cycle IVF combined with in vitro maturation (IVM) of immature oocytes and to determine treatment efficacy. DESIGN Retrospective analysis of IVF treatments. SETTING Hospital IVF clinic. PATIENT(S) Women with infertility according to ovarian reserve and endocrine profile were selected for different treatments. IN...

BACKGROUND Although irregularities in human zona pellucida (ZP) morphology are well described, there is scant literature on the clinical significance of ZP dysmorphology. We, therefore, designed a retrospective cohort trial of ZP dysmorphology to assess the clinical significance of ZP dysmorphology and its affect on IVF outcome. Over the same time period a random sample of 77 cycles of 77 subje...

We present a Bayesian network model for predicting the outcome of in-vitro fertilization (IVF). The problem is characterized by a peculiar missingness process, and we propose a simple but effective averaging approach which improves parameter estimates compared to the traditional MAP estimation. The model can provide relevant insights to IVF experts.

OBJECTIVE To determine whether conversion of high-response gonadotropin/intrauterine insemination (IUI) cycles to "rescue" in vitro fertilization (IVF) yields a higher implantation and pregnancy rate as found in matched IVF controls. DESIGN A prospective study with a retrospective controlled section. SETTING Baskent University Department of Obstetrics and Gynecology. PATIENT(S) Thirty-two...

OBJECTIVE King Fahd University Hospital, Al-Khobar is a tertiary care center without the facility for in-vitro fertilization (IVF) and embryo transfer, but ovulation induction (OI) is done routinely. The objective of this analysis was to study the obstetric outcome of patients who conceived after IVF and OI. DESIGN Retrospective analysis. PATIENTS AND METHODS One hundred and twenty patients...