In the title compound, C13H13NO3, the isoxazole ring is approximately coplanar with the phenyl ring, the dihedral angle between their planes being 7.37 (19)°. In the crystal, centrosymmetrically related mol-ecules are linked into dimers by pairs of C-H⋯O hydrogen bonds, generating a ring of graph-set motif R 2 (2)(10).

In the title compound, C(22)H(30)NO(2)P, the P atom has an irregular tetra-hedral geometry. In the crystal, mol-ecules are connected by N-H⋯O hydrogen-bonding inter-actions, giving rise to a chain along the b axis. The phenyl ring of the anilino group is twisted by 77.40 (16)° relative to the other phenyl ring. The absolute configuration of phospho-rus is S(p).

The present study demonstrates the utility of an in vitro-in vivo correlative approach in the selection of an optimum prodrug candidate of L-767,679 (N-([7-(piperazin-1-yl)-3,4-dihydro-1(1H)-isoquinolinone-2-yl]acetyl)-3(S)-(ethynyl)-beta-alanine), a potent fibrinogen receptor antagonist. As an initial screening step, a comparative in vitro hepatic metabolism study was conducted for L-767,679 a...

For two photochromic isopropyl-thiophenefulgides a complete photokinetic analysis is given. For one compound (Sb), the partial quantum yield for the coloming process (&c= 54%) is the highest value found for thiophenefulgides. EZ-isomerisations do not play an important role. The colouringquantum yield is temperature independent down to 20 K, whereas bleaching requires little thermal activation. ...

The extent of biological inactivation and of the degradation of the RNA after reaction of bacteriophage R17 with ethyl methanesulphonate, isopropyl methanesulphonate and N-ethyl-N-nitrosourea was studied. Formation of breaks in the RNA chain probably results from hydrolysis of phosphotriesters formed in the alkylation reactions. Near neutral pH the ethyl and isopropyl phosphotriesters are suffi...

The title compound, (C(3)H(10)N)(2)[MoS(4)], was synthesized by passing a rapid stream of H(2)S into an aqueous isopropyl-amine solution of molybdic acid. The title compound is isotypic with the corresponding W analogue (C(3)H(10)N)(2)[WS(4)]; its structure consists of a slightly distorted tetra-hedral [MoS(4)](2-) dianion and two crystallographically independent isopropyl-ammonium cations, wit...

In the title compound, C(10)H(9)ClN(2)O(6), the two nitro groups and the ester group are oriented with respect to the benzene ring at dihedral angles of 49.42 (13)/87.61 (13) and 9.10 (10)°, respectively. In the crystal structure, a weak C-H⋯O inter-action is present. A short Cl⋯O contact of 2.972 (2) Å is also observed in the crystal structure.