Dodecyl thioglycosides (3, 4, 5) were prepared by conventional transformation of d-glucose and used as new glycosyl donors for a short-step synthesis of phytoalexin elicitor heptaglucoside. A gentio-tetraoside derivative (6) having three hydroxyl groups was synthesized by NIS-TfOH promoted glycosylate in more than 90% yield followed by selective removal of temporary protective groups. Undesired...

UNLABELLED BACKGROUND Although soybeans have the ability to attenuate insulin resistance, it is insufficient to alleviate type 2 diabetic symptoms and different types of fermented soybeans may have even better anti-diabetic effects. Meju, unsalted fermented soybeans exhibited better insulin sensitizing and insulinotropic actions than unfermented cooked soybeans (CSB). We investigated whether...

We established the adventitious-root cultures of Iris germanica, a monocotyledonous plant known for isoflavonoid production. Irigenin (5,7,3 -trihydroxy-6,4 ,5 -trimethoxyisoflavone) and iristectorigenin A (5,7,3 -trihydroxy6,4 -dimethoxyisoflavone) along with their 7-O-b-D-glucosides, iridin and iristectorin A, respectively, were found as the major components in adventitious roots in the liqui...

Four isoflavone glycosides were isolated from the rhizomes of Iris germanica. Compounds 1 and 2 are new, while compounds 3 and 4 are known isoflavone glycosides. These compounds were identified as iriskashmirianin 4'-O-beta-D-glucoside (1), nigricin 4'-O-beta-D-glucoside (2), irilone 4'-O-beta-D-glucoside (3) and iridin (4). Their structures were determined with the help of spectroscopic methods.

The new isoflavonoid kirkinone A (1) and biflavonoid B (2) along with six known compounds (3–8) were isolated from the methanolic extract of root bark Ochna kirkii. identified by NMR spectroscopic mass spectrometric analyses. Out eight natural products, calodenin (4) lophirone (6) showed significant antibacterial activity against Gram-positive bacterium Bacillus subtilis MIC values 2.2 28 μM, c...

Objectives: We investigated the isoflavone contained in SH003 and its fractions, effect of these components on inhibition breast cancer.Methods: The isoflavones solvent fractions extract were identified by UPLC-MS contents quantified using HPLC analysis. estrogenic activity or was assessed ERE luciferase assay estrogen receptor (ER)-positive MCF-7 cells. To test cancer inhibitory effect, cell v...