BACKGROUND AND PURPOSE Malignant middle cerebral artery infarction is estimated to occur in 10% of ischemic strokes, but few patients undergo decompressive hemicraniectomy, a proven therapy. We determined the proportion of patients with ischemic stroke without significant baseline disability with large middle cerebral artery infarction who would have been potentially eligible for hemicraniectom...

BACKGROUND AND PURPOSE Analysis of quality of care for in-hospital stroke has not been previously performed at the national level. This study compares patient characteristics, process measures of quality, and outcomes for in-hospital strokes with those for community-onset strokes in a national cohort. METHODS We performed a retrospective cohort study of the Get With The Guidelines-Stroke (GWT...

In this paper the neural network model for transient ischemic attacks recognition have been addressed. The proposed approach is based on integration of the NPCA neural network and multilayer perceptron. The dataset from clinic have been used for experiments performing. Combining two different neural networks (NPCA and MLP) it is possible to produce efficient performance in terms of transient is...

BACKGROUND Approximately 25% of ischemic stroke patients awaken with neurological deficits. In these patients, in whom the time from symptom onset is uncertain, brain imaging is a potential strategy to characterize the ischemia duration and the presence of salvageable brain tissue. METHODS We prospectively evaluated consecutive patients with acute ischemic stroke. CT angiography and CT perfus...

#### Notable in Neurology This Week This issue features an article that investigates the association of depression and anxiety with cognitive impairment patients 6 months after stroke; another explores utility olfactory testing screening for Parkinson disease REM behavior disorder. A featured Views & Reviews examines CSF blood neurofilament levels neuronal brain damage athletes who play physic...

background: the aim of this study was to evaluate whether higher serum levels of insulin-like growth factor-i (igf-i) in the acute phase of ischemic stroke are associated with less severe strokes and better functional outcome in a period of 12-month follow-up. methods: from october 2014 to august 2015, patients with the diagnosis of acute ischemic stroke admitted to the stroke unit of firoozgar...

background: changes in the lipid profile have been suggested as a risk factor for developing ischemic stroke. their role in intra-cerebral hemorrhage, however, is not clear. the present study was designed to evaluate the lipid profile levels of patients who had experienced an acute stroke during the first 24-hour and to compare these levels in different patients suffering from the stroke, eithe...

BACKGROUND AND PURPOSE Leukoaraiosis is a radiological finding of uncertain pathogenesis with bilateral patchy or diffuse areas of hyperintensity of the cerebral white matter (WM) on T2-weighted MRI. Using diffusion-weighted MRI (DWI), we aimed to test (1) whether the average apparent diffusion coefficient (ADC(av)) values of the regions of leukoaraiosis vary according to the degree of the seve...

BACKGROUND AND PURPOSE The cause of ischemic stroke remains unclear, or cryptogenic, in as many as 35% of patients with stroke. Not knowing the cause of stroke restricts optimal implementation of prevention therapy and limits stroke research. We demonstrate how gene expression profiles in blood can be used in conjunction with a measure of infarct location on neuroimaging to predict a probable c...

Background and Purpose—The cause of ischemic stroke remains unclear, or cryptogenic, in as many as 35% of patients with stroke. Not knowing the cause of stroke restricts optimal implementation of prevention therapy and limits stroke research. We demonstrate how gene expression profiles in blood can be used in conjunction with a measure of infarct location on neuroimaging to predict a probable c...