Insulin resistance syndrome refers to a group of disorders that are more common in people who Metabolic syndrome, one them such as dyslipidemia. Through alterations insulin metabolic signaling and reductions bioavailable NO, compensatory hyperinsulinemia associated with contributes significantly the pro-inflammatory, pro-oxidative milieu endothelial dysfunction compromises integrity. Objective,...

SEPTEMBER 2010 ADVANCED OCULAR CARE 31 CASE PRESENTATION A 76-year-old white man was referred to our clinic for evaluation of a pigmented lesion that recently increased in size. He had first noticed the abnormal iris pigmentation of his right eye 20 years ago and had been under observation for the previous 5 years. The patient denied any ocular or systemic symptoms; his past medical history was...

TAFRO syndrome is defined by the presence of thrombocytopenia, hydrops, fever, fibrosis, renal dysfunction, and organomegaly can be seen with idiopathic multicentric Castleman disease (iMCD) or as an isolated process without iMCD. The pathophysiology not well understood, but it thought to related hypercytokinemia. Subclinical hypothyroidism may a potential factor in pathogenesis symptomatology ...

Endothelial dysfunction plays an important role in the pathogenesis of cardiovascular diseases. Genetic predisposition, metabolic disorders and other effects, including occupational hazards, can lead to formation endothelial dysfunction. The study aims assess polymorphisms candidate genes development diseases persons with pathology. Scientists have found that carriage certain alleles G894T nitr...

BACKGROUND Recently, novel anatomic parameters that can be measured by optical coherence tomography (OCT), have been identified as a more objective and accurate method of defining the iridocorneal angle. The aim of the present study is to measure the iridocorneal angle by Fourier domain (FD) OCT and to identify correlations between angle measurements and subject factors in a large healthy Cauca...

An increase in the population of patients with diabetes mellitus affects incidence diabetic foot syndrome (DFS), as its chronic complication. Among various types growth factors that play a role development late complications diabetes, vascular endothelial factor, VEGF, is currently focus attention. The study conducted by authors was aimed at determining relationship between G634C polymorphism V...

BACKGROUND Turner Syndrome women are at high risk of vascular disease and the assessment of early risk factors in Turner Syndrome girls is an emerging focus of research. Our objective was to evaluate endothelial function (EF), a preclinical measure of atherosclerosis, in Turner Syndrome girls compared with controls. METHODS A cross-sectional case-control study of Turner Syndrome girls and hea...

Ovarian hyperstimulation syndrome is the most serious iatrogenic complication resulting from ovarian stimulation. Currently there is no clear evidence of absolute efficacy for most of standard preventive and curative methods. Recent studies indicate that human chorionic gonadotropin increases vascular endothelial growth factor, vascular endothelial cadherin and vascular permeability via endothe...

Antiphospholipid syndrome is an important cause of recurrent thrombotic events. The pathogenesis of the thrombosis remains unclear, but it has been suggested that anti-phospholipid Abs, which are laboratory markers for the disease and include species capable of binding to vascular endothelial cells, play an important role. We hypothesized that these anti-endothelial Abs promote thrombosis throu...

Background: Posterior reversible leukoencephalopathy syndrome (PRLS) is a clinical and radiological syndrome of heterogeneous etiologies that are grouped because of the similar findings on neuroimaging studies which may occur at any age. The pathogenesis of RPLS remains unclear, but it appears to be related to disordered cerebral autoregulation and endothelial dysfunction. The syndrome is more ...