Background and objectives: Achillea is an ancient medicinal herb. The genus comprises about 100 species which are mostly distributed in northern hemisphere and some have been investigated for different biological activities. There are also several reports in Iranian Traditional Medicine (ITM) texts about its anti-tumor effect. The cytotoxic activity of the methanol extract of Achillea vermicula...

Iranian Traditional Medicine (ITM) manuscripts contain prescriptions that have long been used for healing of wounds. The present study evaluates the healing effect of a poly herbal paste (PHP), retrieved from ITM sources, containing Aloe vera, Commiphora myrrha and Boswellia carteri using rat excision wound model. Excision wounds were induced in six groups consisting of six rats each. Group 1 r...

CONTEXT Insomnia is one of the most prevalent sleep disorders characterized by sleep difficulty that impairs daily functioning and reduces quality of life. The burden of medical, psychiatric, interpersonal, and societal consequences of insomnia expresses the importance of diagnosing and treatment of insomnia. The aim of study was to investigate causes of insomnia from the viewpoint of Iranian t...

Abstract Background: Atopic dermatitis is a common skin disease associated with chronic inflammation in the skin and itches and most patients have a positive family history of dermatitis. The major treatment of dermatitis, based on allopathic medicine, includes symptomatic treatment by oral antihistamines and topical or oral corticosteroids, which, in lo...

Background and objectives: Recently, deep vein thrombosis (DVT) has remained a major cause of morbidity and death. DVT is a serious public health issue and can be complicated by pulmonary embolism and stroke leading to high economic burden. Disease etiologies may include protein C deficiency, protein S deficiency, factor V Leiden gene mutation, prothrombin gene 20210A mutation,...

In Vol.2, No.1, 2014, Journal of Medical Microbiology and Infection Diseases a paper entitled “Rabies in Iran: Past, Present and Future” was published. We are grateful to Dr. Alireza Gholami and colleagues for this fascinating paper. We read the paper with a great interest but there is one point that should be taken into consideration. The authors have claimed that the discovery of rabies goes ...

background: diabetic foot ulcer is one of the major problems suffered by diabetic patients, so much so that the annual incidence of this problem has increased from 0.1% to 4.1% in diabetic patients and the probability of its incidence is over 25% during the diabetic individual's life. case presentation: the patient was a 74-year-old woman with diabetes for more than 20 years. she was hospi...

Skin hyperpigmentation is characterized as increased production and accumulation of melanin, which could be aesthetically unfavorable and develops serious skin diseases. There is a need to find new depigmenting agents, since many current natural and synthetic products present undesired side effects. In Iranian traditional medicine (ITM), plants have been used for the treatment of skin diseases ...

BACKGROUND Skin is the body's first defense against stressful factors. Skin wounds are caused by the loss of connection in the skin and recovery requires cellular and biochemical reactions. Chronic wounds arise from the lack of physiological processes and the disease due to complications (e.g. infection and amputation) has devastating consequences on societies. According to the principles of Ir...