The large invasion plasmid of Shigella flexneri M9OT-W was used to generate recombinant plasmids carrying the ipaA, -B, -C, and -D genes, whose products are associated with the entry of the bacteria into colonic epithelial cells. Complete DNA sequences of ipaB, -C, and -D were determined. The proteins predicted (62, 42, and 37 kDa, respectively) from the nucleotide sequences lack a signal-pepti...

In this study, polymorphism in ipa genes was found in five out of nine EIEC serotypes studied. When SalI and HindII were used in RFLP-PCR assays many EIEC serotypes showed polymorphism in ipaB and ipaD. On the other hand, no polymorphism was observed in ipaA and ipaC in these strains. The polymorphism present in EIEC strains is serotype-dependent, since restriction patterns were conserved among...

There has been observational evidence about spin axes of quasars in large quasar groups correlated over hundreds Mpc. This is seen the radio spectrum as well optical range. not yet a satisfactory explanation this “spooky” alignment. alignment cannot be explained by mutual interaction at time that manifest themselves optically. A cosmological could possible formation superconducting vortices (co...

I certainly agree with Dr. Melo and colleagues that newer treatments are necessary for the therapy of peripartum cardiomyopathy (PPCM); and particularly in those areas of the world with higher mortality and morbidity rates.1 My hope is to encourage Dr. Melo and colleagues, or others, to carry out a carefully controlled study of either cabergoline or bromocriptine in a large group of subjects wi...

Before the outbreak of COVID-19, case Barcelona was an emblematic example how a city had turned into iconic tourism destination in few decades thanks to smart, yet incautious, development policies based on most attractive features is endowed with. The paper critical reflection analyzing major complications, called “tsunamis”, has faced recent years: political instability, terrorism and tourismo...