background: acute lymphoblastic leukemia (all) constitutes a heterogeneous group of diseases characterized by abnormal proliferation and accumulation of immature lymphoblasts arrested at various differentiation stages. increasing evidence suggests that chromosomal defects are present in these patients. the aim of this study is to investigate the chromosomal radiosensitivity in a group of all pa...

Bacterial endotoxin when injected into mice prior to irradiation will give protection against whole body exposure to ionizing radiation. The greatest degree of protection is conferred when it is administered 24 hours before irradia tion.' Germfree mice withstand higher doses of x-rays than conventional mice2 and still higher doses when administered endotoxin before irradiation. 3 A reduction in...

Ionizing radiation can be effective in controlling the growth of food spoilage and foodborne pathogenic bacteria. This study reports on an investigation of the effectiveness of irradiation treatment to eliminate Listeria monocytogenes on laboratory-inoculated broccoli, cabbage, tomatoes, and mung bean sprouts. Irradiation of broccoli and mung bean sprouts at 1.0 kGy resulted in reductions of ap...

It has been demonstrated that hydrogen can selectively reduce hydroxyl and peroxynitrite in vitro. Since most of the ionizing radiation-induced cellular damage is caused by hydroxyl radicals, this study was designed to test the hypothesis that hydrogen may be an effective radioprotective agent. This paper demonstrates that treating cells with hydrogen before irradiation could significantly inhi...

gamma irradiation is routinely used for suppression of lymphocyte function in transfusion and transplantation procedures. in recent years, some investigators focused on the effects of ionizing radiation on special aspects of lymphocyte function and considered the possibility of its clinical application for treatment of some immunological disorders. in this study, we evaluated the effects of fiv...

Two differently timed extracellular and intracellular enzymatic and mRNA peaks of tissue-type plasrninogen activator (t-PA) were induced following ionizing radiation. The first peak appeared within 10 min following \-irradiation but rapidly declined. The appearance of early tPA mRNA transcripts and enzymatic activity were not prevented by actinomycin D treatment. In contrast, cycloheximide prev...

vide the first line of defense against environmental free radical attack caused by, for example, exposure to UV radiation, ionizing radiation, chemical oxidants, and aerobic microorganisms. Therefore, the skin has developed a complex antioxidant network that includes enzymatic and non-enzymatic components. Prolonged exposure of the skin to UV radiation results in inflammation including erythema...

Little is known about the effects of ionizing radiation on the transition and the related signal transduction of progenitor B cells in the bone marrow. Thus, using an NIH Swiss mouse model, we explored the impact of ionizing radiation on the early stage of B-cell development via an examination of the transition of CLP to pro-B to pre-B cells within bone marrow as a function of radiation doses a...

A quantitative model of the early formation surface states (SS) in MOS structures under ionizing irradiation (II) with a limiting stage --- dispersion transport holes has been developed. According to model, main contribution SS occurs during microsecond pulse II for thin gate dielectric and after end thick field oxide. The increase density is associated presence localized holes. late limited by...

UNLABELLED Extreme radiation-resistant microorganisms can survive doses of ionizing radiation far greater than are present in the natural environment. Radiation resistance is believed to be an incidental adaptation to desiccation resistance, as both hazards cause similar cellular damage. Desert soils are, therefore, promising targets to prospect for new radiation-resistant strains. This is the ...