نتایج جستجو برای: invasive fungal infections
تعداد نتایج: 458280 فیلتر نتایج به سال:
Severe aplastic anemia is almost always fatal unless treated. Invasive fungal infections, particularly those caused by Aspergillus species, have long been recognized as a major cause of death in severe aplastic anemia. However, there are few specific reports about infections and their therapy in patients with aplastic anemia. Despite improvements in the last few years, the response rate of new ...
Chronic granulomatous disease (CGD) is characterized by a defect in phagocytic cells that lead to recurrent bacterial and fungal infections. The etiology of most common fungal infections in CGD are Aspergillus species. Aspergillus nidulans is one of several species of Aspergillus with low pathogenicity. However, it was reported to cause fatal invasive Aspergillosis in patients with CGD. Here we...
BACKGROUND Invasive fungal diseases are important causes of morbidity and mortality. Clarity and uniformity in defining these infections are important factors in improving the quality of clinical studies. A standard set of definitions strengthens the consistency and reproducibility of such studies. METHODS After the introduction of the original European Organization for Research and Treatment...
Estimates of the incidence and prevalence of serious fungal infections, based on epidemiological data, are essential in order to inform public health priorities given the lack of resources dedicated to the diagnosis and treatment of these serious fungal diseases. However, epidemiology of these infections is largely unknown, except for candidaemia and cryptococcosis. The aim of this work is to c...
[Controversies about the management of invasive fungal infections in very low birth weight infants].
OBJECTIVE This review encompasses the most recent publications about fungal infection in very low birth weight infants, keeping health professionals updated about this growing problem observed in neonatal units. SOURCES OF DATA Original and review articles published over the past 15 years were searched in MEDLINE and Lilacs, using the following keywords: preterm infant, very low birth weight ...
In the past decade, the frequency of opportunistic fungal infections has increased, and the spectrum of fungal pathogens has changed. The increasing number of susceptible hosts, the introduction of newer modalities for hematopoietic stem cell transplantation, the evolution of organ transplantation practices, the use of novel immunosuppressive agents, and current antimicrobial prophylactic strat...
Invasive fungal infections are associated with high mortality rates, despite appropriate antifungal therapy. Limited therapeutic options, resistance development and the high mortality of invasive fungal infections brought about more concern triggering the search for new compounds capable of interfering with fungal viability and virulence. In this context, peptides gained attention as promising ...
Aspergillus and Candida are the 2 major sources of invasive mycoses, and deaths due to these infections have been increasing overall during the past 2 decades. Antimicrobial resistance is an important concern, but the extent of resistance among fungi remains largely undefined. Assessing resistance patterns is essential to determine optimal treatment strategies. For invasive Candida infections, ...
The human immune system is capable of recognizing and degrading chitin, an important cell wall component of pathogenic fungi. In the context of host-immune responses to fungal infections, herein we review the particular contributions and interplay of fungus and chitin recognition, and chitin-degrading enzymes, known as chitinases. The mechanisms of host chitinase responses may have implications...
Background: Invasive fungal infections in neutropenic patients treated for
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