نتایج جستجو برای: intravesical instillation

تعداد نتایج: 6985  

2015
Thilo Schwalenberg Frank Peter Berger Lars Christian Horn Phuc Ho Thi Jens‐Uwe Stolzenburg Jochen Neuhaus

BACKGROUND AND OBJECTIVE Intravesical instillation of glycosaminoglycans is a promising option for the treatment of chronic cystitis, as it supports the regeneration of the damaged urothelial layer. We investigated the efficacy of short-term intravesical chondroitin sulphate treatment (six courses of instillation) in patients with chronic radiotherapy- or chemotherapy-associated cystitis. MET...

Journal: :Bratislavske lekarske listy 2000
I Cervenakov K Szoldova J Mardiak D Chovan M Mala D Slavov

OBJECTIVE To ascertain the effect of intravesical instillation of Alpha 2-b Interferon (IFN a-2) 10 million I.U. in 50 ml physiological saline as a monotherapy and in combination with Farmarubicin (FRC) 50 mg dissolved together in 50 ml of physiological saline. These substances were administered four times during the first month after TUR-BT and then once monthly for one year either in the form...

Journal: :Daehan binyogi jong-yang haksulji 2022

Bladder cancer is one of most common malignant urinary tract tumor types, and transurethral resection nonmuscle invasive bladder followed by intravesical instillation immunochemotherapy the standard treatment approach to minimize recurrence delay progression cancer. In general, conventional lacks selectivity for tissues effect drug reduced with excretion urine leading frequent administration ir...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Clement Mugabe Yoshiyuki Matsui Alan I So Martin E Gleave Jennifer H E Baker Andrew I Minchinton Irina Manisali Richard Liggins Donald E Brooks Helen M Burt

PURPOSE The present work describes the development and in vitro and in vivo evaluation of a mucoadhesive nanoparticulate docetaxel (DTX) formulation for intravesical bladder cancer therapy. EXPERIMENTAL DESIGN Mucoadhesive formulations based on hyperbranched polyglycerols (HPG), hydrophobically derivatized with C(8)/C(10) alkyl chains in the core and modified with methoxy-polyethylene glycol ...

2012
Seiya Inoue Motoaki Saito Masashi Honda Fotios Dimitriadis Atsushi Takenaka

Neuropathic bladder dysfunction caused by spinal cord disease may lead to irreversible renal damage and urinary incontinence. The majority of affected children can be successfully managed with standard medical treatment such as oral anti-cholinergic medication (typically oxybutynin or tolterodine) with or without Clean Intermittent Catheterization (CIC). The efficacy of this treatment, however,...

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