Guillain-Barré (GBS) syndrome is an immune-mediated polyneuropathy that frequently presents with progressive muscle weakness. Hyponatremia is rarely the presenting feature of this demyelinating process, as it is normally described following the diagnosis. We report a case of Guillain-Barré syndrome diagnosed after presenting symptoms of severe hyponatremia. Awareness should be raised for consid...

IT has been suggested that anti-basement membrane (BM) antibody is responsible for the development of the pulmonary and the renal lesions in Goodpasture's syndrome (Sturgill and Westervelt, 1965; Beirne, et al, 1968; Willoughby and Dixon, 1970). It is a controversial issue whether this anti-BM antibody is formed by the release of glomerular or alveolar BM antigen. Experimental models resembling...

Pharmacy cost data from the University HealthSystem Consortium (UHC) Clinical Database for specific diagnosis-related groups (DRGs) were reviewed to assess their applicability to a university medical center and to identify opportunities to reduce costs. UHC headquarters was contacted by telephone to determine UHC's data collection methods. Pharmacy costs for DRG 302 (kidney transplant) at the U...

We describe the clinical course of a patient with multiple sclerosis in whom progressive multifocal leukoencephalopathy (PML), an opportunistic viral infection of the central nervous system, developed during treatment with interferon beta-1a and a selective adhesion-molecule blocker, natalizumab. The first PML lesion apparent on magnetic resonance imaging was indistinguishable from a multiple s...

Background: Guillain-Barré syndrome (GBS) is an acute onset immune-mediated disease affecting the peripheral nerve also its root Plasma exchange(PE) and intravenous immuno globulin(IVIG) have given evidence for faster recovery in GBS(4). IVIG treatment comparatively costly but hospital stay duration reduced.Other options include corticosteroids not shown benefit. Mortality of GBS around 3%. Aro...

Since 1992, Human Botulism Immune Globulin has been provided by the California Department of Health Services to infants with probable infant botulism, the intestinal toxemia form of human botulism. Human Botulism Immune Globulin became available in California in 1992–1997 within a randomized, controlled, double-blinded, pivotal clinical trial and subsequently became available nationwide in 1998...

Experimental pneumococcal pneumonia in leukopenic BALB/c mice enabled evaluation of passive immunotherapy with human polyvalent intravenous immune globulin (IVIG) given intravenously or intranasally and with F(ab')2 fragments administered intranasally. For intravenous and intranasal IVIG, the respective effective doses were < 5 but > 0.5 mg/kg and < 250 but > 2.5 micrograms/kg. For F(ab')2 frag...

INTRODUCTION Kawasaki disease is an idiopathic acute systemic vasculitis of childhood. Although it simulates the clinical features of many infectious diseases, an infectious etiology has not been established. This is the first reported case of Kawasaki disease following Rocky Mountain spotted fever. CASE PRESENTATION We report the case of a 4-year-old girl who presented with fever and petechi...

From these three reports, we conclude: 1 Intravenous immune globulin can induce aseptic meningitis in children as well as in adults: the strong temporal association (on day three in our patient and in Watson's patients) and the repetitive occurrence in the same patient (on two occasions in Kato's patient and in our patient) are both strong arguments in favour of this. It should no longer be a h...