OBJECTIVE To compare the efficacy of conventional medical treatment versus transtympanic dexamethasone application into middle ear as treatment modality in Meniere's disease. STUDY DESIGN Prospective randomized study. SETTING Tertiary referral centre. METHOD Forty patients of Meniere's disease were treated, 20 by conventional method and 20 by transtympanic dexamethasone applications. IN...

OBJECTIVE The aim of this study was to assess the efficacy of a single high dose intratympanic (IT) dexamethasone (DEX) as salvage therapy for idiopathic sudden sensorineural hearing loss (ISSNHL) after unsuccessful treatment with oral corticosteroid (CS). MATERIALS AND METHODS This was a prospective open-label study of 59 patients treated with IT DEX after systemic CS therapy has failed. All...

BACKGROUND Ménière's disease is characterised by three major symptoms: vertigo, deafness and tinnitus, which may be accompanied by aural fullness, all of which are discontinuous and variable in intensity. While discontinuous, these symptoms are synchronous. Intratympanic application of gentamicin, an ototoxic aminoglycoside, is a relatively new ablative treatment for vertigo in Ménière's diseas...

UNLABELLED Treatment in sudden sensorineural hearing loss is a contentious issue, today, oral steroids are the most common choice and considered the best treatment option, but the use of intratympanic steroids has become an attractive alternative, especially in cases when systemic therapy fails, or to avoid the side effects of the systemic use of steroids. AIM To describe the results of intra...

The author explains the clinical presentation, pathophysiology, diagnostic work-up, and management of sudden deafness. "Sudden" deafness is defined as sensorineural hearing loss of 30 decibels or more in at least 3 contiguous frequencies occurring over less than 3 days. The pathophysiology of sudden deafness is poorly understood. Various theories have been proposed, including those attributing ...

INTRODUCTION Sudden deafness is characterized by an abrupt onset, often idiopathic and tinnitus is present, and becomes the main complaint in up to 80% of patients. OBJECTIVE To review carefully all studies of the past 10 years on sudden deafness and tinnitus and analyze the effectiveness of oral and intratympanic steroids for tinnitus control in eight patients with sudden deafness and severe...

Idiopathic sudden hearing loss (ISHL) is defined as a sensorineural hearing loss of 30 dB or more at least three contiguous frequencies, which develops over a period of a few hours to 72 hours . Its incidence is 520/100.000 or 4,000 new cases per one year . Almost 98% of the patients are affected unilaterally . Although viral infections, vascular disorders, rupture of cochlear membranes, immuno...

OBJECTIVES/HYPOTHESIS To evaluate the hearing changes and quality-of-life outcomes of 393 cases of streptomycin/dexamethasone inner ear perfusion performed by the primary author on 312 ears of 299 patients with Meniere's disease between July 2002 and May 2010. STUDY DESIGN Retrospective chart review. METHODS Objective arm: A database was used to compile pretreatment and post-treatment audio...