نتایج جستجو برای: intraperitoneal bupivacaine

تعداد نتایج: 23477  

Journal: :Anesthesia and analgesia 2007
Edna Zohar Yossi Noga Uri Rislick Ilan Leibovitch Brian Fredman

One hundred elderly men (> or =65 yr) undergoing transurethral procedures (<45 min) received bupivacaine 7.5 mg, or bupivacaine 5 mg + fentanyl 20 mug, or bupivacaine 4 mg + fentanyl 20 mug, or bupivacaine 3 mg + fentanyl 20 mug, intrathecally. Intraoperative "rescue" fentanyl requirements were higher (P < 0.03) in group bupivacaine 3 mg + fentanyl. Times (min) to ambulation eligibility were de...

2014
Seong Ho Ok Sung Il Bae Seong Chun Kwon Jung Chul Park Woo Chan Kim Kyeong Eon Park Il Woo Shin Heon Keun Lee Young Kyun Chung Mun Jeoung Choi Ju Tae Sohn

BACKGROUND A toxic dose of bupivacaine produces vasodilation in isolated aortas. The goal of this in vitro study was to investigate the cellular mechanism associated with bupivacaine-induced vasodilation in isolated endotheliumdenuded rat aortas precontracted with phenylephrine. METHODS Isolated endothelium-denuded rat aortas were suspended for isometric tension recordings. The effects of nif...

Journal: :Anesthesia and analgesia 2006
Takeshi Yano Shoichiro Ibusuki Mayumi Takasaki

Clinically, lidocaine requires a larger concentration than bupivacaine to block nerves. Bupivacaine has a higher lipid solubility, tissue permeability, and affinity for sodium channels than lidocaine, resulting in greater anesthetic potency. Local anesthetics require access to the sodium channel from the intracellular milieu. In this study, we sought to determine the intracellular concentration...

Journal: :British journal of anaesthesia 2011
K C Cummings D E Napierkowski I Parra-Sanchez A Kurz J E Dalton J J Brems D I Sessler

BACKGROUND Pain after shoulder surgery is often treated with interscalene nerve blocks. Single-injection blocks are effective, but time-limited. Adjuncts such as dexamethasone may help. We thus tested the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia and that the magnitude of the effect differs among the two local anaesthetics....

2012
Farhad Safari Ali Dabbagh Mansour Sharifnia

BACKGROUND There are a number of adjuvants to be used for local anesthetics in spinal block. The aim of this study was to demonstrate the possible effect of intrathecal midazolam compared with bupivacaine as adjuvants in spinal anesthesia with bupivacaine in chronic opium abuses. METHODS In a double blind, randomized clinical trial, 90 opium abuser patients undergoing lower limb orthopedic su...

  Background: Arthroscopic intervention is very common for conducting orthopedic surgeries. After a knee arthroscopic surgery, different drugs are used through intra-articular administration to induce analgesia. The aim of this study was to evaluate analgesic effects of Bupivacaine (marcaine), Bupivacaine plus midazolam, and Bupivacaine plus fentanyl in reducing pain after knee arthroscopic sur...

Journal: :British journal of anaesthesia 1999
V J Palkama P J Neuvonen K T Olkkola

We studied seven healthy volunteers given itraconazole 200 mg orally or placebo, once daily for 4 days, in a crossover study. On day 4, racemic bupivacaine 0.3 mg kg-1 was given i.v. over 60 min and venous plasma samples were collected for 23 h. Plasma concentrations of R- and S-bupivacaine, itraconazole and hydroxyitraconazole were measured. Itraconazole reduced the clearance of R-bupivacaine ...

Journal: :Anesthesia and analgesia 2006
Giovanni Cucchiaro Scott N Adzick John B Rose Lynne Maxwell Mehernoor Watcha

The administration of epidural opioids, though effective for producing analgesia, has severe side effects in most patients. It is unknown whether clonidine can effectively replace opioids and cause fewer side effects. We compared, in this randomized trial, the incidence of vomiting and pruritus as well as the analgesic profile of three different combinations of bupivacaine, fentanyl, and clonid...

2017
Qinqin Yin Jun Li Qingshan Zheng Xiaolin Yang Rong Lv Longxiang Ma Jin Liu Tao Zhu Wensheng Zhang

OBJECTIVE The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal formulation of this combination. METHODS QX-314 and bupivacaine at different concentration ratios were injected in the vicinity of the sciat...

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