To cite: Cuervo-Pardo L, Gonzalez-Estrada A, Fernandez J. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014208980 DESCRIPTION Food is the most common cause of anaphylaxis. Very few cases of mustard seed-induced anaphylaxis have been reported. We present a case of mustard seed anaphylaxis. A 29-year-old man presented to our department for evaluation of anaphylax...

BACKGROUND Cardiac anaphylaxis is accompanied by coronary spasm and decreased left ventricular (LV) contractility. However, it has not been determined experimentally whether LV dysfunction during anaphylaxis is induced mainly by reduced coronary blood flow (CBF) or direct negative inotropic actions of chemical mediators. To demonstrate the major role of CBF reduction in anaphylactic LV dysfunct...

Anaphylaxis is a life-threatening emergency that may be confused with other less serious conditions. The onset of true anaphylaxis typically occurs within minutes following exposure to an offending agent, and it can variably include dyspnea/wheezing, hemodynamic compromise, rash, hives/pruritus, swelling, or gastrointestinal symptoms. absence expected association between exposure(s) classic sym...


 Background: Anaphylaxis is an acutely presenting life-threatening medical emergency. Studies have shown that dentists feel inadequately able to recognize and treat anaphylaxis. This study aims determine the level of knowledge local anesthetic (LA) anaphylaxis among in a Nigerian Teaching Hospital.
 Methods: cross-sectional, questionnaire-based was conducted dental practitioners at D...

Background Anaphylaxis is a potentially life threatening allergic reaction. Failure to identify the inciting allergen places patients at risk of future life-threatening allergen exposure. Anaphylaxis guidelines recommend that all patients who experience anaphylaxis from an allergen encountered in a non-medical setting carry self injectable epinephrine and follow up with an allergist. Very littl...

In the present study, anti-anaphylactic, anti-inflammatory and membrane stabilizing properties of a lupine alkaloid plumerianine (compound 1), isolated from the root bark of Plumeria acutifolia Poir were investigated in animal models. The anti-anaphylactic activity of compound 1 (10, 25 and 50 mg/Kg) was studied by using models such as passive cutaneous anaphylaxis, passive paw anaphylaxis and ...

Anaphylaxis is an acute, life-threatening, systemic reaction with varied clinical presentations and severity that results from the systemic release of mediators from mast cells and basophils. The diagnosis of food-induced anaphylaxis is based on a combination of medical history and presence of specific IgE to the responsible food. In general, the more rapid the onset of symptoms following expos...

1 McDonnell N, Pavy T, Green L, Platt P. Sugammadex in the management of rocuronium-induced anaphylaxis. Br J Anaesth 2011; 106: 199–201 2 Wordsworth H, Raja Y, Harrison S. Sugammadex and rocuronium-induced anaphylaxis. Br J Anaesth 2011; 106: 911–12 3 Rose M, Fisher M. Rocuronium: high risk for anaphylaxis? Br J Anaesth 2001; 86: 678–82 4 Dewachter P, Mouton-Faivre C, Emala C. Anaphylaxis and ...

Since the first description of anaphylaxis in 1902, its clinical importance as an emergency condition has been recognized worldwide. Anaphylaxis is a severe, potentially life-threatening systemic hypersensitivity reaction characterized by rapid onset and potential to endanger life through respiratory or circulatory compromise. It usually, although not always, associated with skin mucosal change...

Sphingosine kinase 1 (SphK1) and SphK2 are ubiquitous enzymes that generate sphingosine-1-phosphate (S1P), a ligand for a family of G protein-coupled receptors (S1PR1-S1PR5) with important functions in the vascular and immune systems. Here we explore the role of these kinases and receptors in recovery from anaphylaxis in mice. We found that Sphk2-/- mice had a rapid recovery from anaphylaxis. I...