Keloid formation is one of the most challenging clinical problems in wound healing. With increasing frequency of open heart surgery, chest keloid formations are not infrequent in the clinical practice. The numerous treatment methods including surgical excision, intralesional steroid injection, radiation therapy, laser therapy, silicone gel sheeting, and pressure therapy underscore how little is...

BACKGROUND Presence of subretinal abscess in endogenous endophthalmitis indicates a more severe form of infection. Available reports indicate variable response to standard treatment with systemic, intravitreal pharmacotherapy and vitreous surgery. There are no reports citing the possible role of intralesional antibiotic therapy in managing subretinal abscess. CASE PRESENTATION A 30 year old l...

OBJECTIVE Describe the management of subglottic stenosis in a patient with Wegener's granulomatosis. MATERIAL AND METHOD Case report. RESULTS We report the case of a 26-year-old woman who presented Wegener granulomatosis and subglottic stenosis, with renal, skin, oropharyngeal, nasal, and paranasal locations. Medical treatment had cured all the locations except the subglottic stenosis. An e...

Introduction. Alopecia areata (AA) is a chronic inflammatory disease that involves hair follicles, and sometimes nails, caused by a T-cell mediated autoimmune mechanism. Current treatment modalities include corticosteroids (oral, topical or intralesional), minoxidil, contact sensitizers (DNCB, DPCP and SADBE), immunosuppressants (methotrexate or azathioprine), DMARDs (sulfasalazine), and photot...

INTRODUCTION: Many studies have proved the role, efficacy and safety profile of intralesional bleomycin in the management of hypertrophic scars and keloids.1 Liposomes, by virtue of their lipid bilayer, have potential to enhance the delivery of drug to the desired area. Drugs encapsulated in liposomes are expected to be transported without rapid degradation and minimum side effects to the recip...

Background: Wart is a common skin disease, and 8% of patients referred to dermatologists suffer from warts. Objective: To compare the efficacy of intralesional injections of bleomycin with normal saline in treatment of common resistant warts on palms and dorsum of hands. Patients & Methods: This study was a double blind, randomized, controlled clinical trial on 34 patients with common war...

BACKGROUND Flagellate hyperpigmentation is a well-documented complication of systemic bleomycin sulfate therapy when using doses of 100 U or more as an antineoplastic agent. Two cases occurred after using systemic doses from 15 to 30 U injected intravenously or intrapleurally; however, it has not been described as a complication following intralesional treatment of verruca plantaris. OBSERVAT...

Introduction: Auricular seroma is a benign condition of the pinna usually following blunt trauma. This condition which presents with a simple swelling of the pinna is occasionally associated with pain and may result in permanent disfigurement of the pinna owing to delay in diagnosis or mismanagement. Various techniques have been proposed and practiced over the years to treat this uncompli...

acute cutaneous leishmaniasis(ACL) is an endemic disease in developing countries.the first line drug for treatment of ACL.according to WHO recommendation,is the pentavalent antimony compounds such as meglumine antimoniate(Glucantime{SB}).high cost ,side effects,multiple injections and incomplete efficacy are limitations of this therapy.we evaluated the efficacy of intralesional(IL) injection of...