OBJECTIVES To evaluate the in vitro leishmanicidal activity of nine flavonoid derivatives from Delphinium staphisagria against L. infantum and L. braziliensis. DESIGN AND METHODS The in vitro activity of compounds 1-9 was assayed on extracellular promastigote and axenic amastigote forms and on intracellular amastigote forms of the parasites. Infectivity and cytotoxicity tests were carried on ...

Results: Response of skin warty lesions to treatment with intralesional 5-FU was as following: complete response was seen in 200 (80.0 %), partial response was seen in 37 (14.8 %) of cases and no response was recorded in 13 (5.2 %) of cases. There was no significant association between size of warty lesion and response to intralesional 5-FU (p = 0.154), but there was significant association bet...

PURPOSE To review the functional outcome and local recurrence rate of 29 patients who underwent segmental excision or intralesional curettage with adjuvant therapy for giant cell tumour (GCT) of bone. METHODS Records of 17 men and 12 women (mean age, 30.17 years) who underwent segmental excision (n=18) or intralesional curettage followed by adjuvant therapy (n=11) for GCT of the femur (n=13),...

INTRODUCTION Incomplete intralesional curettage remains the most important factor contributing to the recurrence of the GCT tumor. A 360 degree view of the tumor cavity can be achieved with the help of an arthroscope, which can aid complete intralesional curettage. CASE REPORT This technical note describes the use of arthroscope assisted curettage of the distal femur GCT. CONCLUSION Use of ...

abstract background glucantime is the first line agent for treatment of cutaneous leishmaniasis (cl). it has adverse effects on blood elements. this research has been done to evaluate the blood complications of this medicine in patients with cutaneous leishmaniasis. methods this clinical trial was done at nikpour clinic, yazd, iran. blood samples were collected from patients diagnosed with cl b...

The causes for the painful heel around the Achilles tendon are Achilles tendinitis and retrocalcaneal bursitis. The treatment modalities range from simple NSAID’s, hot water fomentation, ultrasound phonopheresis, and intralesional steroids to surgery. There is a debate on giving intralesional steroids in and around the Achilles tendon. Most common complication of intralesional corticosteroids i...

background: various responses and different prognosis to specific treatment in different patients from one hand, and importance of ifn-γ producer cells on the other hand impressed us to study tc1. methods: the study was conducted in ghaem medical center and bu-ali research institute, mashhad university of medical sciences, iran from 2001 to 2002. lymphocytes of 36 patients were counted and cult...

background: cutaneous leishmaniasis is an endemic disease in many regions of iran, including the city of mashhad. in recent years, some cases have not responded to glucantime, the usual treatment for this disease. the cellular immune response caused by t-helper type 1 (th1) cells has an important role in protection against leishmaniasis, and activation of the t-helper type 2 (th2) response caus...

PURPOSE This study aims to evaluate the effectiveness of intralesional bleomycin sclerotherapy in the treatment of lymphangioma in children and to determine the incidence of complications in the treatment. METHODS This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. ...

We undertook this retrospective study to determine the rate of recurrence and functional outcome after intralesional curettage for chondroblastoma of bone. The factors associated with aggressive behaviour of the tumour were also analysed. We reviewed 53 patients with histologically-proven chondroblastoma who were treated by intralesional curettage in our unit between 1974 and 2000. They were fo...