BACKGROUND Measurement of fractional flow reserve (FFR) constitutes the current gold standard to evaluate the hemodynamic significance of coronary stenoses. Limited data validate the intracoronary application of adenosine against standard intravenous infusion. We systematically compared FFR measurements during intracoronary and intravenous application of adenosine about agreement and reproducib...

Hepatoportal sclerosis or idiopathic portal hypertension has a worldwide distribution with prevalence in developing and temperate countries. Of 64 patients with this disease seen during a twelve year period, 36 underwent splenectomy or a shunt procedure. The indications for surgical intervention were severe hypersplenism and persistent left upper abdominal pain andlorhistory of frequent ep...

conclusions we found that ei and qp/qs ratio are significantly and positively associated and qp/qs ratio can be easily estimated by measuring ei in secundum type asd patients. background one of the inclusion criteria for applying atrial septal defect (asd) closing procedure is an increased pulmonary-to-systemic blood flow ratio (qp/qs). eccentricity index (ei) is associated with ventricular dys...

fHE CONVENTIONAL coronary angiogram provides :letails of the lumen of the coronary arteries. The mgiogram, however, does not provide information of the structure of the intima, media, and adventitia. With intracoronary ultrasound probes, it is possible to directly obtain information not only of the coronary lumen but also of the type of intraluminal structures and to differentiate cholesterol f...

pulmonary arterial hypertension (pha) is a frequent complication of congenital heart disease (chd), most commonly in systemic-to-pulmonary shunt lesions. in patients with an uncorrected left-to right shunt, pah will end up to eisenmenger’s syndrome, which is contraindication of surgery. what about patients with moderate to severe pah, who do not have criteria of eisenmenger’s syndrome; immediat...

BACKGROUND administration of the glycoprotein IIb/IIIa inhibitor abciximab is an effective adjunctive treatment strategy during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Although small-scale studies have suggested beneficial effects of intracoronary over intravenous administration of abciximab, this has not been investigated in a medium-scale ran...

BACKGROUND Administration of glycoprotein IIb/IIIa inhibitors is an effective adjunctive treatment strategy during primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI). Recent data suggest that an intracoronary administration of these drugs can increase the efficacy of PPCI. This study was done to find any potential difference in terms of effi...

INTRODUCTION AND OBJECTIVES It has been clearly demonstrated that abciximab is useful in percutaneous coronary interventions. However, it is not known if intracoronary administration of the initial abciximab bolus improves outcome. Moreover, there may be safety concerns. METHODS The study was a single-center prospective randomized trial that included all patients undergoing coronary angioplas...