INTRODUCTION Low back pain is a major economical and social problem nowadays. Intervertebral disc herniation and central degeneration of disc are two major reasons of low back pain that occur because of structural impairment of disc. The intervertebral disc contains three parts as follows : Annulus fibrosus, transitional region, and nucleus pulposus, which forms the central nucleus of the disc....

Cauda equina syndrome is a rare but severe neuro-spinal disorder commonly caused due to lumbar disc herniation, which occurs mostly at lower levels of L4-S1. We report case 38-year-old male soldier deployed on foreign mission who presented level 1 military hospital 4 months back with complaints decreased movement bilateral limbs and low pain radiating the right limb for 2 hours. He was referred...

This paper presents the first reported measurements of lumbar intervertebral disc pressure in vivo during spinal manipulation. A pressure transducer was inserted into the nucleus pulposus of one normal-appearing lumbar disc in an asymptomatic adult volunteer. Pressures were recorded during several body positions and maneuvers, then during spinal manipulation, and lastly during a repetition of t...

The aim of the study was to investigate the mechanism of microRNA (miR)-146a-mediated activation of interleukin-6/signal transducer and activator of transcription 3 (IL-6/STAT3) in lumbar intervertebral disc degeneration. To obtain intervertebral tissue, we recruited 5 patients with lumbar intervertebral disc herniation (experimental group) and 5 patients with lumbar burst fracture (control gro...

Bony fusion ofthe anterior part oftwo vertebral bodies is occasionally noted in radiographs of the adult spine, and is usually interpreted as a congenital abnormality or the result of previous infection. It is the author’s belief that it is more commonly a rare manifestation of Scheuermann’s vertebral osteochondritis. The essential lesion in vertebral osteochondritis is the escape of interverte...

We report a cervical intraspinal cyst in a dog that was initially tetraparetic but spontaneously recovered completely. MRI revealed a well-demarcated intraspinal cyst located dorsally to a degenerated intervertebral disc. The location of the cyst and its signal features on MRI resembled those of discal cysts previously reported in humans. It has been reported in dogs that clinical signs of a in...

Lumber disc herniation is one of the most common causes of low back pain. Relevant research indicates that it is generally induced by the degenerated deformation of a disc due to too much labor or spine abnormality. The number and variety of clinical interventions for lumbar disc herniation continue to grow. The lumbar intervertebral disc is a viscoelastic tissue located in the middle of the tw...

Recently, percutaneous epidural neuroplasty has become widely used to treat radicular pain caused by spinal stenosis or a herniated intervertebral disc. A 19-year-old female patient suffering from left radicular pain caused by an L4-L5 intervertebral disc herniation underwent percutaneous epidural neuroplasty of the left L5 nerve root using a Racz catheter. After the procedure, the patient comp...

Intradural disc herniation (IDH) is a rare type of intervertebral disc herniation. It is more common in lumbar region (>90%), however, it has also been known to occur in cervical spine, accounting for less than five percent of cases [1]. The first published case of cervical IDH dates back to 1959 by Morega [2]. To our best knowledge, 35 total cases of cervical are reported following database se...

Repetitive throwing and hitting motions in baseball place mechanical stresses to the lumbar spine which may cause low back pain (LBP). Pain may be due to vertebral stress reactions or insufficiency fractures, intervertebral disc degeneration or intervertebral disc herniation. Untreated chronic conditions have high potential to lead to a more significant injury such as spondylolysis. Chronic LBP...