objective: hypericum perforatum (st. john's wort) has long been used in traditional medicine to treat a variety of internal and external ailments. the present study was done to evaluate the immumodulatory potentials of the hydroalcoholic extract of h. perforatum. materials and methods: twenty male balb/c-mice were randomly allocated in two equal groups and immunized with sheep red blood ce...

BACKGROUND Oligonucleotides belong to a class of macromolecules with great potential for research and various therapeutic applications. Their mechanisms of action are extremely diverse, although they are rather homogeneous in composition. Single-stranded oligodeoxynucleotides are not only inhibitors of gene expression, but their CpG sequence motifs may activate the innate immune response. Recen...

Air refractive index alteration is an important research technique used to examine blast density and pressure. However, precise time-course measurements of changes at a fixed point caused by air waves are challenging due the necessity for high precision noise immunity. This study proposes dual-probe, dual-frequency fiber-optic displacement interferometer that achieves nanometer-level accuracy c...

Solution accuracy of global navigation satellite systems (GNSS) is often compromised by the satellite-user geometry, weak signal levels and system outages. Locata Corporation’s positioning technology potentially bridges such gaps in availability, providing cm-level accuracy in challenging positioning environments. A Locata network consists of timesynchronized terrestrial transceivers (called Lo...

objective: some evidence suggests that chronic uptake of estragole and methyl-eugenol, found in the essential oil of artemisia dracunculus (tarragon), may be associated with an increased risk of hepato-carcinogenicity. the present study was conducted to investigate the immumodulatory and anti-inflammatory potentials of estragole and methyl-eugenol free extract of tarragon. materials and methods...

In response to the problems of low accuracy and poor noise immunity traditional fault diagnosis method for rolling bearing due complex variable operating conditions bearings large interference during signal acquisition, a model based on VMD–RP–CSRN is proposed. Firstly, initial feature extraction carried out by variational modal decomposition (VMD), which then converted into two-dimensional ima...

INTRODUCTION.................................................................. TAXONOMY ..................................................................... MORPHOLOGY ................................................................. STAINING ...................................................................... BIOCHEMISTRY .... RESISTANCE ........................................................

............................................................................................ Preface .............................................................................................. Table of contents ................................................................................. Abbreviations ..................................................................................... C...

Double-stranded RNA (dsRNA) is a common by-product of viral infections and a potent inducer of innate antiviral immune responses in vertebrates. In the marine shrimp Litopenaeus vannamei, innate antiviral immunity is also induced by dsRNA in a sequence-independent manner. In this study, the hypothesis that dsRNA can evoke not only innate antiviral immunity but also a sequence-specific antiviral...

Across metazoans, innate immunity is vital in defending organisms against viral infection. In mammals, antiviral innate immunity is orchestrated by interferon signaling, activating the STAT transcription factors downstream of the JAK kinases to induce expression of antiviral effector genes. In the nematode Caenorhabditis elegans, which lacks the interferon system, the major antiviral response s...