INTRODUCTION Analysis of the annual pesticide poisoning statistics of the Tygerberg Poison Information Centre (TPIC) for the period 2005-2007 showed an increase in the number of amitraz poisonings. This prompted a 2-year survey (2008-2009) to establish the extent of amitraz poisoning in South Africa. Amitraz is a pesticide used as a tick dip. It acts as an α(2)-adrenoceptor agonist and the prin...

Thinners are mixtures of organic solvents commonly containing toluene, xylene, acetone, hexane, benzene and methyl isobutyl ketone. This report describes a case of rhabdomyolysis with acute tubular necrosis and renal failure, most likely attributable to toluene, following occupational exposure to thinners while cleaning a steel water tank. These adverse health effects have previously been repor...

background: this toxicological investigation involves a report on the death of four ‎occupants of a sport utility vehicle on one of the major busy federal roads of nigeria ‎where they were held for up to three hours in a traffic jam while the car was steaming.‎ methods: autopsy was executed using the standard procedure and toxicological ‎analysis was done using simple spectrophotometric method ...

background: closantel is a veterinary drug used as anthelmintic for ruminants while it is contraindicated for humans. this report describes a rare case of blindness, increased liver enzymes and coagulopathy following closantel poisoning. case report: a 5-year-old girl was presented with acute blindness following closantel poisoning. she was given mistakenly a dose of 500 mg/day (25mg/kg/day) fo...

background: lidocaine is a local anesthetic and antiarrhythmic agent. there are reports on accidental and intentional cases of poisoning following injection of lidocaine while rare are the fatal cases realized after oral ingestion of lidocaine. suicidal poisoning with lidocaine pharmaceutical formulations is rare since no pharmaceutical dosage forms for oral use are available except gels and sp...

BACKGROUND Prevalence of alcohol-related harms in England are among the highest in Europe and represents an important policy issue. Understanding how alcohol-related trends vary by demographic factors is important for informing policy debates. The aim of our study was to examine trends in alcohol-related admissions to hospital in England, with a focus on variations by sex, age and socioeconomic...

Exposure to pesticides has been the source of many acute and chronic health problems in the rural population, mainly in developing countries. The objective of this study was to characterize the poisonings from acute exposure to agricultural pesticides used in the state of Mato Grosso do Sul, Brazil, from 1992 to 2002, which were reported to the Integrated Center of Toxicological Vigilance of th...

Brake oil is a type of hydraulic fluid used in automobiles. It consists toxic compounds like ethylene glycol, diethyleneglycol and additives. poisoning rare it can either be due to intentional or accidental1,2. Toxic manifestations are mainly metabolites rather than the brake oil3,4. Immediate haemodialysis other supportive carecan improve outcome intoxicated patients. Here we present case repo...

BACKGROUND Most official mortality publications do not present the mechanism of injury (for example, cut/pierce, drowning, fall, poisoning, or suffocation) for intentional injuries (for example, suicide or homicide). OBJECTIVES To determine if the presentation of mechanism of injury for intentional injuries had different mechanism profiles. METHODS Age adjusted injury mortality rates by int...

Objective: The objective of this study is to use a new data set to compare the circumstances of fatal poisoning in deaths ruled as suicides to those ruled as unintentional, particularly with regard to the prevalence of mental health, substance abuse, and other risk factors. Design: The design is an analysis of all fatal poisonings using data from the New Jersey Violent Death Reporting System. P...