*Department of Microbiology and Immunology et al., 1995) and adhesion molecules (very late antigen School of Medicine 4) (Yang et al., 1993). University of North Carolina at Chapel Hill Studies of rodent models and preliminary studies in Chapel Hill, North Carolina 27599 man have shown that the completion of b cell destruc†Department of Microbiology and Immunology tion can beconsiderably delaye...

Background Decision-makers have begun to recognize Health-Related Quality of Life (HRQoL) as an important and measurable outcome of healthcare interventions; and HRQoL data is increasingly being used by policy-makers to prioritize health resources. Our objective was to measure HRQoL in a group of Type 2 Diabetes Mellitus (T2DM) patients receiving insulin treatment in Buenos Aires, Argentina.   ...

The ultimate goal for those who care for people with insulin dependent diabetes is prevention. This seemed a futile quest until the 1 970s when the aetiology ofthe condition began to be unravelled. Insulin dependent diabetes mellitus was shown to be an autoimmune disorder with a genetic basis, strongly associated with the class II alleles DR3 and DR4. This led to a series of studies of immunosu...

conclusions it seems that in people with type 2 diabetes, acute aerobic exercise can decrease the plasma levels of glucose, possibly through increasing orexin a. in addition, negative energy balance is necessary to decrease the levels of insulin and insulin resistance during acute aerobic exercise. results the analysis of findings in p ≤ 0.05 indicated that acute aerobic exercise caused a signi...

BACKGROUND The objective of this study was to identify the impact of diabetes and related comorbidities, namely chronic renal failure, peripheral vascular disease, and low ejection fraction (<35%), on long-term survival of patients undergoing coronary artery bypass graft surgery. METHODS AND RESULTS A unicenter study was conducted on 9125 survivors of isolated coronary artery bypass graft sur...

OBJECTIVES We sought to determine whether the antioxidant vitamin C improves endothelium-dependent vasodilation of forearm resistance vessels in patients with insulin-dependent diabetes mellitus. BACKGROUND Endothelium-dependent vasodilation is impaired in patients with diabetes mellitus. Oxidatively mediated degradation of endothelium-derived nitric oxide contributes to abnormal endothelium-...

Diabetes mellitus (DM) is mainly characterized by hyperglycemia [1] with an imbalance of carbohydrate, protein and fat metabolism due to reduced production of insulin from pancreas (defects in insulin secretion), or when insulin cannot be used efficiently by the body (defect in insulin action), or both [1,2]. Two major forms of diabetes are Type I DM (TIDM) and Type II DM (TIIDM). TIDM is also ...