The authors examined the associations of toenail selenium levels with blood concentrations of fibrinogen, high-sensitivity C-reactive protein (hs-CRP), and interleukin-6 (IL-6) in an 18-year follow-up study comprising 4,032 Americans aged 20-32 years at baseline (1987) from the Coronary Artery Risk Development in Young Adults (CARDIA) Trace Element Study. Toenail samples were collected in 1987,...

The association between several cancers and selenium status has been investigated in epidemiological studies. However, few results concerning bladder cancer have been reported thus far. The association between toenail selenium status and subsequent bladder cancer incidence was investigated in a prospective cohort study among 120,852 men and women aged 55-69 years at baseline (September 1986). T...

This prospective study evaluated the relationship between long-term dietary habits and total arsenic (As) concentration in toenail clippings in a cohort of 1616 pregnant women in the Bangladeshi administrative regions of Sirajdikhan and Pabna Sadar. Diet was assessed at Gestation Week 28 and at Postpartum Month 1, using a locally-validated dish-based semi-quantitative food-frequency questionnai...

This study examined the concentration of heavy metal accumulated in the toenail of welders and compared to the concentration of airborne heavy metal exposure in the breathing zone of the welders. Ten selected welders with adequate toenail growth were asked to clip all ten toenails for analysis. The heavy metal concentration in the welder’s breathing zone was collected by using mixed cellulose e...

BACKGROUND This research was conducted to confirm the validity and reliability and to assess the responsiveness and clinical meaningfulness of the OnyCOE-t, a questionnaire specifically designed to measure patient-reported outcomes (PRO) associated with toenail onychomycosis. METHODS 504 patients with toenail onychomycosis randomized to receive 12 weeks of terbinafine 250 mg/day with or witho...

To the Editor: Onychomycosis is a chronic fungal nail infection affecting an estimated 0.35% to 5.5% of children worldwide,1Gupta A.K. Mays R.R. Versteeg S.G. et al.Onychomycosis in children: safety and efficacy antifungal agents.Pediatr Dermatol. 2018; 35: 552-559Crossref PubMed Scopus (12) Google Scholar although parents health care practitioners are hesitant use long-term systemic treatments...

Several conservative as well as surgical methods are used for the treatment of ingrown toenails until date. The conservative methods are either based on nail splinting or on orthonyxia, but no methods employing both principles have been reported thus far. Moreover, surgical methods usually involve postoperative pain, prolonged wound healing and restricted activities of daily living. Therefore, ...

Ulcerative Dermatitis (UD) is the most common cause of unplanned euthanasia in mice used in research, with prevalence rates reported between 4 and 21%. UD is characterized by a deep, ulcerative lesion that appears most commonly over the dorsal neck and is attendant with an intense pruritus. The underlying cause of UD is currently unknown, and as a consequence, there are no directed therapies th...

BACKGROUND In Vietnam, environmental pollution caused by small-scale domestic smelting of automobile batteries into lead ingot is a growing concern. The village of Nghia Lo is a smelting craft village located roughly 25 km southeast of Hanoi in the Red River Delta. Despite the concern of toxic metal exposure in the village, biomonitoring among susceptible populations, such as children, has not ...

background and purpose: it is important to follow annually the probable changes in distribution pattern of dermatophytosis and its etiological agents in different communities. in this study, we determined the prevalence of dermatophytosis and its causative agents in damascus, syria, between 2008 and 2016. materials and methods: a total of 4080 outpatients who visited the dermatological clinics ...