Plus II Infusion Pump is unique in several important respects. First, according to Abbott, by 2000, this device was the market leader, was used around the world, and accounted for about 75% of all PCA use in the U.S., being used in nearly 4,000 hospitals there.3,4 Furthermore, in 2001, ECRI (formerly the Emergency Care Research Institute, www.ecri.org) stated "this pump has a significant safety...

dministering cancer chemotherapy by continuous intravenous infusion (CIVI) has several potential advantages over administration by short intravenous infusions1 and has been facilitated by the development of portable infusion pumps.2 In a study by Wilson et al.,3 the EPOCH regimen—etoposide, prednisone, vincristine, cylophosphamide, and doxorubicin—was shown to be highly effective and well toler...

Dentists often sedate patients in order to reduce their dental phobia and stress during dental treatment. Sedatives are administered through various routes such as oral, inhalation, and intravenous routes. Intravenous administration has the advantage of rapid onset of action, predictable duration of action, and easy titration. Typically, midazolam, propofol or dexmedetomidine are used as intrav...

Intraspinal drug delivery (IDD) has been increasingly utilized since 1980s, initially in patients with cancer pain, and subsequently in patients with intractable, chronic, nonmaligmant pain. By infusing a small amount of opioid into the cerebrospinal fluid in close proximity to the receptor sites in the spinal cord, profound analgesia may be achieved while sparing some of the side effects due t...