نتایج جستجو برای: inferiority feelings
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Unfortunately, the original version of this article [1] contained an error. The correct paragraph can be found below: The calculation of number of patients was not correct. It was wrote the non-inferiority margin as 0.1 mm. But it was 0.19 mm in an original document. Non-inferiority margin in previous coronary intervention studies has been set between 0.1 ~ 0.2 mm. The 0.19 mm is not irrelevant...
BACKGROUND Subjects with breast cancer enrolled in trials may experience multiple events such as local recurrence, distant recurrence or death. These events are not independent; the occurrence of one may increase the risk of another, or prevent another from occurring. The most commonly used Cox proportional hazards (Cox-PH) model ignores the relationships between events, resulting in a potentia...
In drug development, non-inferiority tests are often employed to determine the difference between two independent binomial proportions. Many test statistics for non-inferiority are based on the frequentist framework. In this paper, we propose a method for the determination of sample sizes using the index ( ) , , 2 1 0 2 1 X X P ∆ − π > π = τ where 1 X and 2 X denote binomial random variables fo...
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