In comparison to tablets drug loaded pellets exhibit the advantageous properties of multiparticulate drug delivery systems. After administration homogeneous distribution in the gastrointestinal tract takes place, drug is released over a large area avoiding concentration peaks, and bioavailability is improved. Up to this time the number of market products with drug coated inert pellets manufactu...

Activated tungsten inert gas welding (ATIG) is a new approach to Tungsten Inert Gas (TIG) that has the potential improve weld penetration. This paper investigates effect of micro and nanoparticle size oxide flux during TIG Hastelloy C-22. The SiO<sub>2</sub> Al<sub>2</sub>O<sub>3</sub> fluxes in terms particle thermal stability on surface appearance, bead geo...

Axial segregation behaviour of a single biomass particle in lab-scale bubbling fluidized bed has been investigated from both experimental and modelling perspectives. Experiments were conducted using beech wood particles different sizes, ranging 8 to 12 mm under either oxidizing or inert conditions. The reactor was operated at temperatures fluidization velocity ratios, U/Umf, the range 500–650 °...

For many fluidized bed applications, the particle movement inside reactor is accompanied by reactions at scale. The current study presents for first time in literature a multi-scale modelling approach coupling one-dimensional volumetric model with dense discrete phase (DDPM) of ANSYS Fluent via user defined functions. To validate developed approach, uses experimental data pressure drop, tempera...

The role of the airway circulation in supporting mucociliary function has been essentially unstudied. We evaluated the airway clearance of inert, insoluble particles in anesthetized ventilated sheep (n = 8), in which bronchial perfusion was controlled, to determine whether airway mucosal blood flow is essential for maintaining surface transport of particles through airways. The bronchial branch...

We present a new definition of the concept of representation for cognitive science that is based on a study of the origin of structures that are used to store memory in evolving systems. This study consists of novel computer experiments in the evolution of cellular automata to perform nontrivial tasks as well as evidence from biology concerning genetic memory. Our key observation is that repres...