We have addressed the hypothesis that Notch ligands play a decisive role in determining the ability of antigen-presenting cells to influence T cell polarization. Dendritic cells displayed distinct expression profiles of Delta and Jagged ligands for Notch when exposed to biologically relevant pathogen preparations associated with Th1 or Th2 responses. Expression of delta4 was increased, and jagg...

Transcription factors act in concert to induce lineage commitment towards Th1, Th2, or T regulatory (Treg) cells, and their counter-regulatory mechanisms were shown to be critical for polarization between Th1 and Th2 phenotypes. FOXP3 is an essential transcription factor for natural, thymus-derived (nTreg) and inducible Treg (iTreg) commitment; however, the mechanisms regulating its expression ...

The plasmid DNA encoding the fliC gene of Burkholderia pseudomallei combined with CpG oligodeoxynucleotide (ODN) was injected intramuscularly into BALB/c mice, resulting in the increased production of certain humoral antibodies and flagellin-specific spleen cell clonal expansion. CpG ODN, as an immunoadjuvant, was added to the plasmid containing the fliC gene in order to obtain ongoing expressi...

We theoretically investigate the interaction of an ultrastrong femtosecond-long linearly polarized optical pulse with AB-stacked bilayer graphene. The excite electrons from valence into conduction band, resulting in finite band population. Such a redistribution results generation current which can be manipulated by angle incidence pulse. For normal incidence, along direction transverse to polar...

This Perspective concerns the latest developments in field of chiral nanocrystals (NCs) and metastructures, focusing primarily on plasmonic nanostructures. Such nanomaterials exhibit unusually strong near-field electromagnetic responses that enable efficient biosensing light manipulation. Herein we share our thoughts trends mark what call a paradigm shift for vast dynamic chiroptical materials....

Abstract The measurement and manipulation of the microwave polarization emitted from a frequency-agile 198 GHz gyrotron for dynamic nuclear (DNP) are demonstrated. In general, gyrotrons emit linearly polarized radiation, yet in this case elliptical is observed window. Indeed, half power circularly while other with 60 ∘ respect to horizontal plane. For optimal use DNP experiments, converted into...

The effects of solution concentration and temperature on the electrochemical behavior Fe-based amorphous (AMCs) coatings in NaCl were studied by using conventional measurement XPS analysis. Results indicated that as increased, current density for AMCs increased pitting potential decreased. This reduced corrosion resistance was derived from decreased passivation index polarization resistance, wh...

we study copper corrosion inhibition by ethanolamine (eta)with (0, 0.2 ,0.3,0.4,0.5) vol.% concentrations in 100 ppm nacl solution. this work is carried out by potentiodynamic measurements and electrochemical impedance spectroscopy (eis). the substrates' surface morphologies are examined by scanning electron microscopy (sem). etais characterized by nmr spectra of eta1h and 13c and fourier ...

A coupled polarization-matrix inversion and iteration (CPII) method is described to achieve and accelerate the convergence of induced dipoles for condensed phase systems employing polarizable intermolecular potential functions (PIPF). The present PIPF is based on the Thole interaction dipole model in which all atomic pair interactions are considered, including those that are directly bonded cov...