background: diabetes is considered as one of the most common chronic disease. studies show that diabetes decreases the activity of antioxidant enzymes. the purpose of this study was to examine the effect of the alcoholic extract of juglans regia leave on brain antioxidant enzymes in streptozotocin-induced diabetic rats. materials and methods: in this study, adult male wistar rats (n=40, weight ...

introduction: there is evidence that diabetes affects seizure susceptibility. ginger (zingiber officinale roscoe) which is used in traditional medicine has antioxidant activity and neuroprotective effects. the aim of this study was to evaluate the seizure threshold induced by pentylenetetrazole (ptz) in diabetic mice after induction of diabetes with streptozocin and to examine the possible role...

Diabetes osteoporosis is a common secondary bone Metabolic disorder, which seriously affects the quality of life patients. Traditional Chinese medicine categorizes it as "diabetes" combined with "bone dysfunction". Through consulting related literature diabetes induced osteoporosis, this paper summarized TCM understanding disease, etiology and pathogenesis, syndrome differentiation treatment, c...

objective(s) since diabetes mellitus is accompanied by cognitive impairment in diabetic patient and animal models and since lipids play important roles in neuronal membrane composition, structure and function; we intended to evaluate the effect of dietary butter oil on passive avoidance memory of streptoztosin (stz)-induced diabetic rats in this study. materials and methods thirty six adult mal...

background: overexpression of lectin-like low density lipoprotein (lox-1) receptor plays an important role in hyperglycemia-induced vascular complications such as atherosclerosis. based on the beneficial effects of exercise on preventing cardiovascular complications of diabetes, we aimed to examine the protective effects of aerobic exercise on expression of lox-1 receptor and production of free...

objective: arctium lappa (burdock), (a. lappa) root has hypoglycemic and antioxidative effects, and has been used for treatment of diabetes in tradition medicine. this study was conducted to evaluate the antidiabetic and hypolipidemic properties of a. lappa root extract on nicotinamide-streptozotocin (na-stz)-induced type2 diabetes in mice.materials and methods: in this investigation, 70 adult ...

Background & Aims: Numerous studies have reported the renoprotective effects of exercise in both human and animal models of diabetic nephropathy. However, detailed mechanism of action by which exercise has a favorable influence on renal fibrogenic factors is not yet fully understood. Therefore, the aim of this study was to assess the effect of swimming exercise on the activity ...

Introduction: Diabetes mellitus is a metabolic disorder and it is estimated that its annual incidence rate will continue to increase in the future worldwide. Increased oxidant factors and decreased antioxidant defense are two of the factors resulting in diabetes. In the present study, we aimed to investigate Citrullus Colocynthis pulp effects on oxidant and antioxidant factors of liver in st...

purpose: the purpose of the current study is to evaluate the efficacy of regular exercise as a useful nonpharmacological strategy in attenuating the diabetes symptom such as hyperglycaemia, polyuria, polydipsia, polyphagia, and weight loss. materials and methods: twenty male wistar rats (200±20 gr) were divided to four groups (n = 5 per group): sedentary normal (n), trained normal (ne), sedenta...

Nano-sized drugs have better distribution than their identical forms. Magnesium is the cofactor of various enzymes in lipid and glucose metabolism. In this study the effect of nano-magnesium oxide (nano-MgO) on glucose concentration and lipid profile in diabetes induced mice was evaluated in 21 laboratory mice. Mice were divided randomly into three equal groups (control, treatment and placebo)....