Anterior cruciate ligament (ACL) reconstruction surgery has significantly evolved in recent years. This has led to development of new technologies that facilitate the diagnosis of ACL injury and the application of state of the art methods for treatment. In particular, individualized anatomical ACL reconstruction aims to restore native ACL function. Treatment is tailored to each patient based on...

A scheme of classification is suggested for physicians faced with clinicians' numerous and varied prescriptions for remedial management of children with learning disabilities. Three explanatory models of the causes of learning disability -- the difference, deficit and delay models -- and two strategies of management -- the process-oriented and goal-oriented -- are delineated. Remedial methods a...

User modeling is employed by applications that need to maintain explicit models of their users in order to exhibit individualized behaviour. The user modeling task involves representation and acquisition of assumptions about the user. Particularly user model acquisition is closely related to the machine learning task of automatically acquiring new information as well as new representations of e...

In E-learning, there is still the problem of knowing how to ensure an individualized and continuous learner‟s follow-up during learning process, indeed among the numerous tools proposed, very few systems concentrate on a real time learner‟s follow-up. Our work in this field develops the design and implementation of a Multi-Agents System Based on Dynamic Case Based Reasoning which can initiate l...

The major problem of e-learning is often stopped during training. Due to the fact that it is necessary to ensure an individualized and continuous learner’s follow-up during the learning process. Our work in this field develops the design and implementation of a Multi-Agents System Based on Dynamic Case Based Reasoning which can initiate learning and provide an individualized follow-up of a lear...

personalized medicine is significantly changing the fundamentals of healthcare. genetic diagnostic tests are used in various parts of medicine – from initial screening to the diagnosis and finally treatment. investigations in fields of drug development indicate that oncology may lead other therapeutic areas in the number of targeted therapies on the marketplace as well as in the pipeline, expec...

Individualized treatment effect lies at the heart of precision medicine. Interpretable individualized rules (ITRs) are desirable for clinicians or policymakers due to their intuitive appeal and transparency. The gold-standard approach estimating ITRs is randomized experiments, where subjects different groups confounding bias minimized extent possible. However, experimental studies limited in ex...