BACKGROUND The cost-effectiveness of the optimal use of hospital-based acute myocardial infarction (AMI) treatments and their potential impact on coronary heart disease (CHD) mortality in China is not well known. METHODS AND RESULTS The effectiveness and costs of optimal use of hospital-based AMI treatments were estimated by the CHD Policy Model-China, a Markov-style computer simulation model...

BACKGROUND Abciximab reduces the number of ischemic events in patients undergoing angioplasty compared to standard therapy. Coronary stenting reduces the need for repeat procedures. Abciximab or stents individually are considered cost effective interventions. There is a need to quantify the economic value of the combination of abciximab and stenting over stenting alone. METHODS A decision ana...

OBJECTIVE To compare the cost-effectiveness of eflornithine and melarsoprol in the treatment of human African trypanosomiasis. METHOD We used data from a Médecins Sans Frontières treatment project in Caxito, Angola to do a formal cost-effectiveness analysis, comparing the efficiency of an eflornithine-based approach with melarsoprol. Endpoints calculated were: cost per death avoided; incremen...

OBJECTIVES To determine the incremental net health benefits of dabigatran etexilate 110 mg and 150 mg twice daily and warfarin in patients with non-valvular atrial fibrillation and to estimate the cost effectiveness of dabigatran in the United Kingdom. DESIGN Quantitative benefit-harm and economic analyses using a discrete event simulation model to extrapolate the findings of the RE-LY (Rando...

BACKGROUND In the absence of major contraindications, treatment guidelines recommend that, following a major traumatic event, all patients receive low molecular weight heparin (e.g. enoxaparin) as thromboprophylaxis for the prevention of deep vein thrombosis (DVT). OBJECTIVE To estimate the incremental cost-effectiveness of enoxaparin versus low dose unfractionated heparin (UH) for the prophy...

Background We evaluated the cost-effectiveness of nivolumab versus everolimus in patients with advanced renal cell carcinoma (RCC) from a US payer perspective. Methods A partitioned survival model consisting of three health states, progression-free survival (PFS), progressive disease, and death, was developed to evaluate the cost-effectiveness of intravenous nivolumab versus oral everolimus o...

aspirin is one of the certified medicines commonly used for the secondary prevention of myocardial infarction (mi). aspirin side effects and gastrointestinal bleeding, in particular, have arisen debates on its use for the primary prevention of mi. the present research evaluates the cost-effectiveness of the use of aspirin in the primary prevention of mi among iranian men with average cardiovasc...

introduction: in recent years, a few studies have been conducted in the area of the cost-effectiveness of the eplerenone; it's notable that coherent and clear evidence are not available. therefore, this study aimed to systematically review studies of cost-effectiveness of eplerenone in the treatment of cardio-vascular patients. methods: this systematic review study was conducted in 2016. t...

background the increase in high-risk injections and unsafe sexual behaviors has led to increased hiv infection prevalence among intravenous drug users (idus). the high costs of hiv/aids care and low financial resources necessitate an economic evaluation to make the best decision for the control of hiv/aids. objectives this study was conducted to determine the cost-effectiveness of methadone mai...

OBJECTIVE To evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners' care. METHODS A multicentre randomised trial with 175 community dwelling patients newly diagnosed with mild to moderate dementia, and their informal caregivers, with twelve months' follow-up. Cost-effectiveness was evaluated from a soc...